Telangiectasia macularis eruptiva perstans, a form of cutaneous mastocytosis, associated with malignant melanoma

Summary A 62‐year‐old obese woman presented with a malignant melanoma (Stage la). In addition, she had disseminated telangiectatic macules on both thighs. Intensive rubbing of lesions resulted in wheals. Biopsy revealed increased numbers of mast cells. We diagnosed telangiectasia macularis eruptiva...

Full description

Saved in:
Bibliographic Details
Published in:Journal der Deutschen Dermatologischen Gesellschaft 2009-04, Vol.7 (4), p.360-362
Main Authors: Kowalzic, Lutz, Eickenscheidt, Lena, Seidel, Christoph, Kribus, Sabine, Ziegler, Heidrun, Komar, Michael
Format: Article
Language:English
Subjects:
cutaneous mastocytosis
c‐kit
Female
Humans
malignant melanoma
Mastocytosis, Cutaneous - complications
Mastocytosis, Cutaneous - pathology
Melanoma - complications
Melanoma - pathology
Middle Aged
Skin Neoplasms - complications
Skin Neoplasms - pathology
telangiectasia macularis eruptiva perstans
Telangiectasis - complications
Telangiectasis - pathology
urticaria pigmentosa
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary A 62‐year‐old obese woman presented with a malignant melanoma (Stage la). In addition, she had disseminated telangiectatic macules on both thighs. Intensive rubbing of lesions resulted in wheals. Biopsy revealed increased numbers of mast cells. We diagnosed telangiectasia macularis eruptiva perstans, a rare clinical form of adult maculopapular cutaneous mastocytosis, a group which also includes urticaria pigmentosa. No evidence was found for systemic involvement. Possible associations with malignant tumors and the possible role of c‐kit mutations both in development of melanoma and mastocytosis are discussed.
ISSN:1610-0379
1610-0387
DOI:10.1111/j.1610-0387.2008.06941.x