Evaluation of cytocompatibility and bending modulus of nanoceramic/polymer composites

In an attempt to simulate the microstructure and mechanical properties of natural bone, novel nanoceramic/polymer composite formulations were fabricated and characterized with respect to their cytocompatibility and mechanical properties. The bending moduli of nanocomposite samples of either poly(L‐l...

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Bibliographic Details
Published in:Journal of biomedical materials research. Part A 2005-01, Vol.72A (1), p.98-106
Main Authors: McManus, Anastasia J., Doremus, Robert H., Siegel, Richard W., Bizios, Rena
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
bending modulus
Biocompatible Materials - chemistry
Biocompatible Materials - pharmacology
Cell Adhesion
Cells, Cultured
Ceramics - chemistry
Ceramics - pharmacology
composites
cytocompatibility
Materials Testing
Mechanics
nanoceramics
Nanotechnology
osteoblasts
Osteoblasts - cytology
Osteoblasts - drug effects
poly(L-lactic acid)
poly(methyl methacrylate)
Polymers - chemistry
Polymers - pharmacology
Prostheses and Implants
Rats
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Summary:In an attempt to simulate the microstructure and mechanical properties of natural bone, novel nanoceramic/polymer composite formulations were fabricated and characterized with respect to their cytocompatibility and mechanical properties. The bending moduli of nanocomposite samples of either poly(L‐lactic acid) (PLA) or poly(methyl methacrylate) (PMMA) with 30, 40, and 50 wt % of nanophase (
ISSN:1549-3296
1552-4965
DOI:10.1002/jbm.a.30204