Osteosarcomas of the Larynx

Objectives/Hypothesis: The objective was to review the etiology, presentation, treatment, and prognosis in patients with osteosarcoma of the larynx using an illustrative case example. Study Design: Case report and literature review. Methods: A case is reported, and a review of all available publishe...

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Bibliographic Details
Published in:The Laryngoscope 2005-01, Vol.115 (1), p.74-77
Main Authors: Athré, Raghu S., Vories, Andrew, Mudrovich, Steven, Ducic, Yadranko
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Diseases of the osteoarticular system
Female
Humans
Laryngeal Neoplasms - diagnosis
Laryngeal Neoplasms - pathology
Larynx cancer
Medical sciences
osteoid
osteosarcoma
Osteosarcoma - diagnosis
Osteosarcoma - pathology
Otorhinolaryngology. Stomatology
Tumors of striated muscle and skeleton
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Summary:Objectives/Hypothesis: The objective was to review the etiology, presentation, treatment, and prognosis in patients with osteosarcoma of the larynx using an illustrative case example. Study Design: Case report and literature review. Methods: A case is reported, and a review of all available published cases of osteosarcoma of the larynx is presented. Results: Osteosarcoma of the larynx may be a difficult clinical diagnosis. To be able to reach the correct diagnosis, a high index of suspicion and due diligence in obtaining deep biopsy specimens are important. Treatment is primarily surgical. Outcomes for this disease are generally poor, with most patients dying of the disease as a result of pulmonary metastasis. Conclusion: Osteosarcoma of the larynx is a rare entity, with only 14 cases reported to date. Pathological confirmation of osteoid is required for diagnosis. It is likely that aggressive surgical intervention directed at complete tumor extirpation is the treatment of choice, although long‐term prognosis is poor.
ISSN:0023-852X
1531-4995
DOI:10.1097/01.mlg.0000150672.45484.5c