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Bedside assessment of fibrinogen level in postpartum haemorrhage by thrombelastometry
Objectives To establish whether reagent‐supported thrombelastometry with the rotation thrombelastometry system (ROTEM®) point‐of‐care device correlated with fibrinogen level in postpartum haemorrhages. Design Prospective observational study. Population and setting Ninety‐one women at the third tr...
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Published in: | BJOG : an international journal of obstetrics and gynaecology 2009-07, Vol.116 (8), p.1097-1102 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Objectives To establish whether reagent‐supported thrombelastometry with the rotation thrombelastometry system (ROTEM®) point‐of‐care device correlated with fibrinogen level in postpartum haemorrhages.
Design Prospective observational study.
Population and setting Ninety‐one women at the third trimester of pregnancy: 37 with postpartum haemorrhage (study group) and 54 without abnormal bleeding (control group).
Methods Standard laboratory test results were compared with those obtained at bedside from the ROTEM with the FIBTEM® test (54 tests in the control group and 51 in the study group).
Main outcome measures Analysis of correlations between fibrinogen levels and FIBTEM test results: clotting time (CT), clot amplitude at 5 and 15 minutes (CA5; CA15) and maximal amplitude [maximum clot firmness (MCF)].
Results Median fibrinogen level was significantly lower in the haemorrhage group than in the control group (3.4 and 5.1 g/l, respectively, P |
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ISSN: | 1470-0328 1471-0528 |
DOI: | 10.1111/j.1471-0528.2009.02187.x |