Surgical therapy for metastatic disease to the liver

The liver is a common site of hematogenous metastasis. In the past, patients with liver metastases were often deemed inoperable, and medical therapy conferred only minor survival benefit. However, advances in surgical techniques and chemotherapeutic agents during the past two decades have led to eff...

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Bibliographic Details
Published in:Annual review of medicine 2005-01, Vol.56 (1), p.139-156
Main Authors: Bentrem, David J, Dematteo, Ronald P, Blumgart, Leslie H
Format: Article
Language:English
Subjects:
Carcinoma, Neuroendocrine - drug therapy
Carcinoma, Neuroendocrine - mortality
Carcinoma, Neuroendocrine - surgery
Chemotherapy
Chemotherapy, Adjuvant
Colorectal cancer
Colorectal Neoplasms - drug therapy
Colorectal Neoplasms - mortality
Colorectal Neoplasms - surgery
Combined Modality Therapy
Feasibility Studies
Hepatectomy
Hepatitis
Humans
Liver
Liver Neoplasms - drug therapy
Liver Neoplasms - mortality
Liver Neoplasms - secondary
Liver Neoplasms - surgery
Surgery
Survival Rate
Urogenital Neoplasms - drug therapy
Urogenital Neoplasms - mortality
Urogenital Neoplasms - surgery
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Summary:The liver is a common site of hematogenous metastasis. In the past, patients with liver metastases were often deemed inoperable, and medical therapy conferred only minor survival benefit. However, advances in surgical techniques and chemotherapeutic agents during the past two decades have led to effective treatments for selected patients with metastases to the liver. Up to approximately 80% of the liver can be resected, and partial hepatectomy is now routinely performed with a perioperative mortality rate of
ISSN:0066-4219
1545-326X
DOI:10.1146/annurev.med.56.082103.104630