Nefopam or clonidine in the pharmacologic prevention of shivering in patients undergoing conscious sedation for interventional neuroradiology

Summary The aim of this randomised, double‐blind study was to investigate the usefulness of intravenous nefopam, clonidine or placebo in preventing shivering in patients undergoing conscious sedation for interventional neuroradiological procedures. A total of 101 patients were prospectively enrolled...

Full description

Saved in:
Bibliographic Details
Published in:Anaesthesia 2005-02, Vol.60 (2), p.124-128
Main Authors: Bilotta, F., Ferri, F., Giovannini, F., Pinto, G., Rosa, G.
Format: Article
Language:English
Subjects:
Adult
Aged
Analgesics - pharmacology
Analgesics, Non-Narcotic - pharmacology
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Pressure
Clonidine - pharmacology
Conscious Sedation - adverse effects
Double-Blind Method
Ephedrine - administration & dosage
Female
Heart Rate
Humans
Male
Medical sciences
Middle Aged
Nefopam - pharmacology
Neurology
Neuroradiography
Pharmacology
Prospective Studies
Radiology, Interventional
Severity of Illness Index
Shivering - drug effects
Shivering - physiology
Vasoconstrictor Agents - administration & dosage
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary The aim of this randomised, double‐blind study was to investigate the usefulness of intravenous nefopam, clonidine or placebo in preventing shivering in patients undergoing conscious sedation for interventional neuroradiological procedures. A total of 101 patients were prospectively enrolled and assigned to one of three groups to receive nefopam, clonidine or placebo. The overall incidence of intra‐operative shivering was significantly lower in patients treated with nefopam than in those treated with clonidine or placebo (2/32 (6%) vs. 11/38 (29%), p 
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.2004.04032.x