Comparative Studies on the Hypolipidemic and Growth Suppressive Effects of Oolong, Black, Pu-erh, and Green Tea Leaves in Rats

• Published in: Journal of agricultural and food chemistry 2005-01, Vol.53 (2), p.480-489
• Main Authors: Kuo, Kuan-Li, Weng, Meng-Shih, Chiang, Chun-Te, Tsai, Yao-Jen, Lin-Shiau, Shoei-Yn, Lin, Jen-Kun
• Format: Article
• Language: English
• Subjects: Animals; Biological and medical sciences; black tea; blood lipids; Body Weight - drug effects; Camellia sinensis - chemistry; Catechin - analysis; cholesterol; Cholesterol - blood; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Coffee, tea and other stimulative beverage industries; Diet; extracts; Food industries; Fundamental and applied biological sciences. Psychology; green tea; Growth Inhibitors - administration & dosage; high density lipoprotein; Hypolipidemic Agents - administration & dosage; leaves; lipemic effect; low density lipoprotein; Male; oolong tea; oral administration; Plant Leaves - chemistry; pu-erh tea; Rats; Rats, Sprague-Dawley; Superoxide Dismutase - blood; tea; triacylglycerols; Triglycerides - blood; weight gain
• ISSN: 0021-8561; 1520-5118
• DOI: 10.1021/jf049375k

The four major commercial teas, oolong, black, pu-erh, and green teas, have been manufactured in southeast Asia. In this study, we evaluated the growth suppressive and hypolipidemic effect of these four different tea leaves by oral feeding to male Sprague−Dawley rats for 30 weeks. The results showed that the suppression of body weights of tea leaves-fed groups were in the order:  oolong tea > pu-erh tea > black tea > green tea. Pu-erh tea and oolong tea could lower the levels of triglyceride more significantly than that of green tea and black tea, but pu-erh tea and green tea were more efficient than oolong tea and black tea in lowering the level of total cholesterol. In lipoprotein, 4% pu-erh tea could increase the level of HDL-C and decrease the level of LDL-C, but other teas simply decrease the levels of both. The activity of antioxidant enzyme SOD is increased in all tea-fed groups as compared to the basal diet-fed group. Finally, relative weight ratios of liver to epididylmal adipose tissue were lower in feeding oolong tea and pu-erh tea groups. On the basis of these findings, it seemed that the fully fermented pu-erh and black tea leaves and partially fermented oolong tea leaves were more effective on their growth suppressive and hypolipidemic effects as compared to the nonfermented green tea leaves. Keywords: Gowth suppressive; hypolipodemic; triglyceride; total cholesterol; HDL-C; LDL-C