Associations of Polymorphic Variant of MnSOD Gene with Breast Cancer in Residents of the Altai Region

The incidence of MnSOD genotypes in residents of the Altai Region suffering from breast cancer and individuals without a history of cancer corresponded to the Hardy-Weinberg equilibrium. No association of MnSOD with the incidence of sporadic breast cancer was detected. No association of MnSOD, tobac...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2009, Vol.147 (1), p.84-87
Main Authors: Kostrykina, N. A, Pechkovskiy, E. A, Boyarskikh, U. A, Sushko, A. G, Voronina, E. N, Lazarev, A. F, Petrova, V. D, Zarubina, N. A, Selezneva, I. A, Sinkina, T. V, Terekhova, S. A, Filipenko, M. L
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Base Sequence
Biomedical and Life Sciences
Biomedicine
breast neoplasms
Breast Neoplasms - enzymology
Breast Neoplasms - genetics
Case-Control Studies
Cell Biology
DNA Primers
Female
Humans
Internal Medicine
Laboratory Medicine
Middle Aged
MnSOD
Oncology
Pathology
Polymerase Chain Reaction
Polymorphism, Genetic
Siberia
SOD2
Superoxide Dismutase - genetics
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Summary:The incidence of MnSOD genotypes in residents of the Altai Region suffering from breast cancer and individuals without a history of cancer corresponded to the Hardy-Weinberg equilibrium. No association of MnSOD with the incidence of sporadic breast cancer was detected. No association of MnSOD, tobacco smoking, or menopausal status, on the one hand, and breast cancer development, on the other, was detected.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-009-0442-1