Flip-flop of glycosylphosphatidylinositols (GPI's) across the ER

The transbilayer flip-flop of early intermediates in the glycosylphosphatidylinositol (GPI) biosynthetic pathway has been demonstrated using novel fluorescent GPI probes and a biochemical reconstitution approach.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2005-01 (4), p.453-455
Main Authors: Vishwakarma, Ram A, Menon, Anant K
Format: Article
Language:English
Subjects:
Biochemical Phenomena
Biochemistry
Endoplasmic Reticulum - chemistry
Endoplasmic Reticulum - metabolism
Glycosylphosphatidylinositols - biosynthesis
Glycosylphosphatidylinositols - chemistry
Lipid Bilayers - chemistry
Lipid Bilayers - metabolism
Models, Chemical
Molecular Probes
Molecular Structure
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Description
Summary:The transbilayer flip-flop of early intermediates in the glycosylphosphatidylinositol (GPI) biosynthetic pathway has been demonstrated using novel fluorescent GPI probes and a biochemical reconstitution approach.
ISSN:1359-7345
1364-548X
DOI:10.1039/b413196g