Late occurrence of bilateral tuberculous-like epididymo-orchitis after intravesical bacille Calmette-Guérin therapy for superficial bladder carcinoma

We report a case of bilateral tuberculous-like epididymo-orchitis occurring 3 years after intravesical bacille Calmette-Guérin instillation therapy in an 83-year-old patient with proven superficial bladder carcinoma. The patient had no previous history of tuberculosis. Because of persistent inflamma...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2005, Vol.65 (1), p.175-175
Main Authors: Falkensammer, C., Gozzi, C., Hager, M., Maier, H., Bartsch, G., Höltl, L., Rehder, P.
Format: Article
Language:English
Subjects:
Adenocarcinoma - radiotherapy
Adenocarcinoma - surgery
Administration, Intravesical
Aged
Aged, 80 and over
BCG Vaccine - administration & dosage
BCG Vaccine - adverse effects
Carcinoma in Situ - therapy
Carcinoma, Transitional Cell - therapy
Combined Modality Therapy
Epididymitis - etiology
Epididymitis - surgery
Humans
Instillation, Drug
Male
Mycobacterium bovis - isolation & purification
Neoplasms, Multiple Primary
Orchiectomy
Orchitis - etiology
Orchitis - surgery
Prostatic Neoplasms - radiotherapy
Prostatic Neoplasms - surgery
Time Factors
Transurethral Resection of Prostate
Tuberculoma - etiology
Tuberculoma - surgery
Tuberculosis, Male Genital - etiology
Tuberculosis, Male Genital - surgery
Urinary Bladder Neoplasms - therapy
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Summary:We report a case of bilateral tuberculous-like epididymo-orchitis occurring 3 years after intravesical bacille Calmette-Guérin instillation therapy in an 83-year-old patient with proven superficial bladder carcinoma. The patient had no previous history of tuberculosis. Because of persistent inflammation and painful swelling of the epididymides and testes, the patient underwent bilateral orchiectomy. This case demonstrates the late adverse effects that can occur after intravesical BCG therapy, which in our patient ended in surgical removal of both gonads.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2004.07.027