Angiographic and clinical outcomes associated with direct versus conventional stenting among patients treated with fibrinolytic therapy for ST-elevation acute myocardial infarction

The present study reports outcomes of direct stenting versus conventional stenting, which was performed during adjunctive/rescue percutaneous coronary intervention (n = 556) in the Integrilin and Tenecteplase in Acute Myocardial Infarction trial, the Enoxaparin as Adjunctive Antithrombin Therapy for...

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Bibliographic Details
Published in:The American journal of cardiology 2005-02, Vol.95 (3), p.383-386
Main Authors: Ly, Hung Q., Kirtane, Ajay J., Buros, Jacki, Giugliano, Robert P., Popma, Jeffrey J., Antman, Elliot M., Harrington, Robert A., Ohman, E. Magnus, Gibson, C. Michael
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Clinical Trials as Topic
Coronary Angiography
Coronary heart disease
Data Interpretation, Statistical
Female
Fibrinolytic Agents - therapeutic use
Heart
Heart Failure - prevention & control
Humans
Male
Medical sciences
Middle Aged
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - drug therapy
Myocardial Infarction - surgery
Myocarditis. Cardiomyopathies
Stents
Thrombolytic Therapy
Treatment Outcome
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Summary:The present study reports outcomes of direct stenting versus conventional stenting, which was performed during adjunctive/rescue percutaneous coronary intervention (n = 556) in the Integrilin and Tenecteplase in Acute Myocardial Infarction trial, the Enoxaparin as Adjunctive Antithrombin Therapy for ST-Elevation Myocardial Infarction–Thrombolysis in Myocardial Infarction 23 trial, and the Fibrinolytic and Aggrastat ST-Elevation Resolution trial of fibrinolytic therapy in ST-elevation myocardial infarction. Direct stenting was associated with a lower rate of death, myocardial infarction, or congestive heart failure during hospitalization and at 30 days and was independently associated with improved in-hospital outcomes (odds ratio 0.44, 95% confidence interval 0.23 to 0.85, p = 0.014).
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.09.038