Next Generation, High Relaxivity Gadolinium MRI Agents

The strong expansion of medical magnetic resonance imaging (MRI) has prompted the development of a new class of pharmacological products, called contrast agents. The image-enhancing capability of a contrast agent is directly proportional to its relaxation of neighboring water molecules by the parama...

Full description

Saved in:
Bibliographic Details
Published in:Bioconjugate chemistry 2005, Vol.16 (1), p.3-8
Main Authors: Raymond, Kenneth N, Pierre, Valérie C
Format: Article
Language:English
Subjects:
Drug Stability
Gadolinium - chemistry
Hydrogen-Ion Concentration
Image Enhancement - methods
Ions
Magnetic Resonance Imaging - methods
Magnetic Resonance Imaging - trends
Molecular Structure
NMR
Nuclear magnetic resonance
Organometallic Compounds - chemistry
Pharmacology
Pyridones - chemistry
Stereoisomerism
Water - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The strong expansion of medical magnetic resonance imaging (MRI) has prompted the development of a new class of pharmacological products, called contrast agents. The image-enhancing capability of a contrast agent is directly proportional to its relaxation of neighboring water molecules by the paramagnetic ion.
ISSN:1043-1802
1520-4812
DOI:10.1021/bc049817y