Progress of multiple cutaneous and subcutaneous melanoma metastases of the face during imiquimod treatment

Summary A 68‐year‐old man developed a local recurrence with multiple cutaneous and subcutaneous nodules three months after excision of a primary malignant melanoma of the temple. Despite extensive surgery and adjuvant irradiation, another local recurrence occurred. Following further local progressio...

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Bibliographic Details
Published in:Journal der Deutschen Dermatologischen Gesellschaft 2009-06, Vol.7 (6), p.538-540
Main Authors: Kowalzick, Lutz, Eickenscheidt, Lena
Format: Article
Language:English
Subjects:
Aged
Aminoquinolines - therapeutic use
Antineoplastic Agents - therapeutic use
chemotherapy
Facial Neoplasms - drug therapy
Facial Neoplasms - secondary
Fatal Outcome
Humans
Imiquimod
immunotherapy
Male
malignant melanoma
Melanoma - drug therapy
Melanoma - secondary
radiotherapy
Skin Neoplasms - drug therapy
Treatment Failure
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Summary:Summary A 68‐year‐old man developed a local recurrence with multiple cutaneous and subcutaneous nodules three months after excision of a primary malignant melanoma of the temple. Despite extensive surgery and adjuvant irradiation, another local recurrence occurred. Following further local progression during dacarbazine chemotherapy, topical treatment with imiquimod was begun and the chemotherapy was changed to fotemustine. During this treatment further local progression occurred and two months later regional lymph node and distant metastasis were detected. The patient died from his tumor disease eighteen months after the first diagnosis of malignant melanoma.
ISSN:1610-0379
1610-0387
DOI:10.1111/j.1610-0387.2009.07041.x