MDCT venography in the evaluation of inferior vena cava in Budd-Chiari syndrome

• Published in: Indian journal of gastroenterology 2009, Vol.28 (1), p.17-23
• Main Authors: Virmani, Vivek, Khandelwal, Niranjan, Kang, Mandeep, Gulati, Madhu, Chawla, Yogesh
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Angiography, Digital Subtraction; Budd-Chiari Syndrome - diagnostic imaging; Child; Constriction, Pathologic; Female; Gastroenterology; Hepatic Veins - diagnostic imaging; Hepatology; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Original Article; Phlebography - methods; Prospective Studies; Sensitivity and Specificity; Statistics, Nonparametric; Tomography, X-Ray Computed; Vena Cava, Inferior - diagnostic imaging; Vena Cava, Inferior - pathology; Young Adult
• ISSN: 0254-8860; 0975-0711
• DOI: 10.1007/s12664-009-0004-5

Objective To assess the role of multidetector computed tomography (MDCT) venography in the evaluation of the inferior vena cava (IVC) in Budd-Chiari syndrome (BCS), its accuracy as compared to digital subtraction venography (DSV) and the potential of this technique to replace venography for the definitive diagnosis of BCS. Methods Twenty-five suspected cases of BCS were prospectively enrolled in this study and underwent both MDCT venography and DSV. Two observers independently evaluated and graded both the axial and reformatted MDCT images for the presence, site, degree and length of IVC narrowing. The collateral pathways and the hepatic veins were also assessed in all cases. The degree of correlation between MDCT venography and DSV was expressed using Spearman’s rank correlation coefficient (Rs). Results There was excellent correlation between MDCT venography and DSV in predicting the presence of stenosis and in grading the degree and length of IVC stenosis (Rs=0.58, p