Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines

[Display omitted] Various 2,4,6-tri substituted s-triazines were synthesized and screened for antibacterial activity against Gram-positive and Gram-negative organisms. These s-triazine derivatives displayed high in vitro antibacterial activities comparable to penicillin and streptomycin against test...

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 2005-02, Vol.15 (4), p.1121-1123
Main Authors: Srinivas, K., Srinivas, U., Rao, V. Jayathirtha, Bhanuprakash, K., Kishore, K. Hara, Murty, U.S.N.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemical synthesis
Anti-Bacterial Agents - pharmacology
Antibacterial activity
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal activity
Biological and medical sciences
Gram-Negative Bacteria - drug effects
Gram-Positive Bacteria - drug effects
Humans
Medical sciences
Microbial Sensitivity Tests
Pharmacology. Drug treatments
s-Triazines
Structure-Activity Relationship
Synthesis
Triazines - chemical synthesis
Triazines - pharmacology
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Summary:[Display omitted] Various 2,4,6-tri substituted s-triazines were synthesized and screened for antibacterial activity against Gram-positive and Gram-negative organisms. These s-triazine derivatives displayed high in vitro antibacterial activities comparable to penicillin and streptomycin against tested microorganisms.
ISSN:0960-894X
1464-3405
DOI:10.1016/j.bmcl.2004.12.020