Nephrostomy insertion for patients with bilateral ureteric obstruction caused by prostate cancer

Ureteric obstruction causing renal failure is a serious complication of advanced prostate cancer. Percutaneous nephrostomies (PCNs) are used to decompress the obstructed kidney(s). This study aims to identify whether bilateral PCN insertion confers any advantage over unilateral PCN insertion for pat...

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Bibliographic Details
Published in:British journal of radiology 2009-07, Vol.82 (979), p.571-576
Main Authors: NARICULAM, J, MURPHY, D. G, JENNER, C, SELLARS, N, GWYTHER, S, GORDON, S. G, SWINN, M. J
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Creatinine - metabolism
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Nephrostomy, Percutaneous - methods
Prostatic Neoplasms - blood
Prostatic Neoplasms - complications
Retrospective Studies
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
Survival Analysis
Treatment Outcome
Ureteral Obstruction - blood
Ureteral Obstruction - etiology
Ureteral Obstruction - pathology
Ureteral Obstruction - surgery
Urinary system involvement in other diseases. Miscellaneous
Urinary tract. Prostate gland
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Summary:Ureteric obstruction causing renal failure is a serious complication of advanced prostate cancer. Percutaneous nephrostomies (PCNs) are used to decompress the obstructed kidney(s). This study aims to identify whether bilateral PCN insertion confers any advantage over unilateral PCN insertion for patients with bilateral ureteric obstruction. In a cohort of 25 patients, 18 underwent bilateral and 7 underwent unilateral PCN insertion. The mean survival time following PCN was 7.5 months for all patients. The data suggest that the nadir serum creatinine after PCN insertion was similar, independent of whether one or two nephrostomies were inserted. There was also little difference in the serum creatinine levels at the time of death, suggesting that survival after PCN insertion is based on the aggressiveness of the prostate cancer as opposed to the number of nephrostomies inserted.
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr/38306763