Prevention of human immunodeficiency virus mother–to–child transmission in Israel

The objective of the study was to investigate the HIV-mother-to-child transmission (MTCT) rate in Israel. This was a retrospective study of HIV-infected pregnant women, mainly immigrants from Ethiopia, in six Israeli AIDS centres, in 2000–2005. Medical records of mothers and newborns were evaluated...

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Bibliographic Details
Published in:International journal of STD & AIDS 2009-07, Vol.20 (7), p.473-476
Main Authors: Agmon-Levin, N, Elbirt, D, Asher, I, Torten, D, Cohen, Y, Gradestein, S, Werner, B, Turner, D, Chowers, M, Gottesman, G, Maayan, S, Risenberg, K, Levi, I, Sthoeger, Z
Format: Article
Language:English
Subjects:
Adolescent
Adult
AIDS/HIV
Anti-HIV Agents - therapeutic use
Antiretroviral Therapy, Highly Active
Biological and medical sciences
Emigrants and Immigrants
Epidemiology. Vaccinations
Ethiopia
Female
General aspects
HIV Infections - epidemiology
HIV Infections - prevention & control
HIV Infections - transmission
HIV Infections - virology
Human viral diseases
Humans
Infant, Newborn
Infectious Disease Transmission, Vertical - prevention & control
Infectious Disease Transmission, Vertical - statistics & numerical data
Infectious diseases
Israel - epidemiology
Medical sciences
Middle Aged
National Health Programs
Nevirapine - therapeutic use
Pregnancy
Pregnancy Complications, Infectious - drug therapy
Pregnancy Complications, Infectious - epidemiology
Pregnancy Complications, Infectious - virology
Program Evaluation
Reverse Transcriptase Inhibitors - therapeutic use
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral Load
Young Adult
Zidovudine - therapeutic use
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Summary:The objective of the study was to investigate the HIV-mother-to-child transmission (MTCT) rate in Israel. This was a retrospective study of HIV-infected pregnant women, mainly immigrants from Ethiopia, in six Israeli AIDS centres, in 2000–2005. Medical records of mothers and newborns were evaluated for HIV status, treatment and MTCT rates. Three hundred pregnancies of 241 HIV-infected women, resulting in 304 live births, were studied. In 86/241(36%) women, HIV diagnosis was made during the current pregnancy or shortly after labour. Thirty others were diagnosed during previous pregnancies. Highly active antiretroviral therapy (HAART) was prescribed in 76% of pregnancies. The mean viral load before labour was 23,000 ± 100,000 copies/mL with a mean CD4 of 406 ± 223 (range 4–1277) cells/mm3. Caesarian sections were preformed in 175/300 pregnancies (103/175 with viral load
ISSN:0956-4624
1758-1052
DOI:10.1258/ijsa.2008.008392