Arterio-embolic ischemic stroke in children with moyamoya disease

Moyamoya (MM) disease is a rare steno-occlusive cerebrovascular disease known to occur in children and adults. The most serious complications in children are developmental delay and mental retardation due to recurrent hemodynamic stroke. We report two pediatric patients without coagulopathy who suff...

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Bibliographic Details
Published in:Child's nervous system 2005-02, Vol.21 (2), p.104-107
Main Authors: Horn, Peter, Bueltmann, Eva, Buch, Christoph V, Schmiedek, Peter
Format: Article
Language:English
Subjects:
Anterior Cerebral Artery - pathology
Anterior Cerebral Artery - physiopathology
Cerebral Angiography - methods
Child
Diffusion Magnetic Resonance Imaging - methods
Humans
Male
Moyamoya Disease - complications
Moyamoya Disease - drug therapy
Moyamoya Disease - pathology
Stroke - etiology
Stroke - pathology
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Summary:Moyamoya (MM) disease is a rare steno-occlusive cerebrovascular disease known to occur in children and adults. The most serious complications in children are developmental delay and mental retardation due to recurrent hemodynamic stroke. We report two pediatric patients without coagulopathy who suffered from severe arterio-embolic ischemic complications despite antiplatelet medication. These observations underline the potential impact of cerebral thromboembolism on the pathophysiology of the stroke and thus on the treatment of children with MM disease.
ISSN:0256-7040
1433-0350
DOI:10.1007/s00381-004-0962-y