Proton MRS of the peritumoral brain

• Published in: Journal of the neurological sciences 2005-02, Vol.228 (2), p.137-142
• Main Authors: Chernov, Mikhail F., Kubo, Osami, Hayashi, Motohiro, Izawa, Masahiro, Maruyama, Takashi, Usukura, Masao, Ono, Yuko, Hori, Tomokatsu, Takakura, Kintomo
• Format: Article
• Language: English
• Subjects: Adult; Aspartic Acid - analogs & derivatives; Aspartic Acid - analysis; Aspartic Acid - metabolism; Biological and medical sciences; Biomarkers, Tumor - analysis; Biomarkers, Tumor - metabolism; Brain - metabolism; Brain - pathology; Brain - physiopathology; Brain Edema - etiology; Brain Edema - metabolism; Brain Edema - physiopathology; Brain Neoplasms - diagnosis; Brain Neoplasms - metabolism; Brain Neoplasms - physiopathology; Brain tumor; Epilepsy - etiology; Epilepsy - metabolism; Female; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Investigative techniques, diagnostic techniques (general aspects); Lactate; Lactic Acid - analysis; Lactic Acid - metabolism; Magnetic Resonance Spectroscopy; Male; Medical sciences; Middle Aged; N-Acetylaspartate; Neoplasm Recurrence, Local; Nerve Fibers, Myelinated - metabolism; Nerve Fibers, Myelinated - pathology; Nervous system; Nervous system (semeiology, syndromes); Neurology; Peritumoral brain edema; Predictive Value of Tests; Proton MRS; Protons; Radiodiagnosis. Nmr imagery. Nmr spectrometry
• ISSN: 0022-510X; 1878-5883
• DOI: 10.1016/j.jns.2004.11.039

Long-echo (TR: 2000 ms, TE: 136 ms) proton MRS of the cerebral tissue in the vicinity to intracranial lesion was done in 15 patients, mainly with parenchymal brain tumors. Significant decrease of N-acetylaspartate (NAA) ( P