P2Y12 Receptors Play a Significant Role in the Development of Platelet Microaggregation in Patients with Diabetes

Ninety-eight diabetic patients (type 2) were studied together with 24 healthy normotensive controls. Microaggregates (particle scale,

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2005-02, Vol.90 (2), p.920-927
Main Authors: Matsuno, Hiroyuki, Tokuda, Haruhiko, Ishisaki, Akira, Zhou, Yuan, Kitajima, Yasuo, Kozawa, Osamu
Format: Article
Language:English
Subjects:
Adenosine Diphosphate - pharmacology
Adenosine Monophosphate - analogs & derivatives
Adenosine Monophosphate - pharmacology
Aged
Biological and medical sciences
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - physiopathology
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Female
Fundamental and applied biological sciences. Psychology
Humans
Male
Medical sciences
Membrane Proteins - drug effects
Membrane Proteins - physiology
Middle Aged
Piperazines - pharmacology
Piperidines - pharmacology
Platelet Aggregation - drug effects
Platelet Aggregation - physiology
Purinergic P2 Receptor Antagonists
Receptors, Purinergic P2 - drug effects
Receptors, Purinergic P2 - physiology
Receptors, Purinergic P2Y12
Reference Values
Vertebrates: endocrinology
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Description
Summary:Ninety-eight diabetic patients (type 2) were studied together with 24 healthy normotensive controls. Microaggregates (particle scale,
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2004-0137