Streptogramins, Oxazolidinones, and Other Inhibitors of Bacterial Protein Synthesis

Mukhtar and Wright address the structure, mode of action, and resistance to the streptogramin and oxazolidinone antibiotics, two distinct classes of antibiotics that have recently been brought to market for treatment of bacterial infections.

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Bibliographic Details
Published in:Chemical reviews 2005-02, Vol.105 (2), p.529-542
Main Authors: Mukhtar, Tariq A, Wright, Gerard D
Format: Article
Language:English
Subjects:
Antibiotics
Bacterial Proteins - biosynthesis
Drug Resistance, Bacterial
Molecular Structure
Oxazolidinones - chemistry
Oxazolidinones - pharmacology
Oxazolidinones - therapeutic use
Protein Biosynthesis - drug effects
Protein Synthesis Inhibitors - chemistry
Protein Synthesis Inhibitors - pharmacology
Protein Synthesis Inhibitors - therapeutic use
Streptogramins - chemistry
Streptogramins - pharmacology
Streptogramins - therapeutic use
Structure-Activity Relationship
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Description
Summary:Mukhtar and Wright address the structure, mode of action, and resistance to the streptogramin and oxazolidinone antibiotics, two distinct classes of antibiotics that have recently been brought to market for treatment of bacterial infections.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr030110z