Laparoscopic versus open myomectomy—A meta-analysis of randomized controlled trials

Abstract The objective of this study was to determine the better method of myomectomy by comparing laparoscopic and open myomectomy for patients with fibroids with regard to operative parameters and outcomes. A systematic review was performed on published studies identified by the databases PubMed,...

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Published in:European journal of obstetrics & gynecology and reproductive biology 2009-07, Vol.145 (1), p.14-21
Main Authors: Jin, Chu, Hu, Yan, Chen, Xia-chan, Zheng, Fei-yun, Lin, Feng, Zhou, Kai, Chen, Feng-di, Gu, Hang-zhi
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Digestive system. Abdomen
Endoscopy
Female
Gynecologic Surgical Procedures - methods
Gynecology. Andrology. Obstetrics
Humans
Investigative techniques, diagnostic techniques (general aspects)
Laparoscopic
Laparoscopy
Laparotomy
Leiomyoma - surgery
Medical sciences
Meta-analysis
Middle Aged
Myomectomy
Obstetrics and Gynecology
Open
Randomized Controlled Trials as Topic
Treatment Outcome
Uterine Neoplasms - surgery
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Summary:Abstract The objective of this study was to determine the better method of myomectomy by comparing laparoscopic and open myomectomy for patients with fibroids with regard to operative parameters and outcomes. A systematic review was performed on published studies identified by the databases PubMed, EMBASE, the China Biological Medicine Datadase (CBMdisc), Ovid and the Cochrane Library, as well as cross-references. Randomized controlled trials on laparoscopic versus open myomectomy were assessed on operative parameters and outcomes. Six studies and 576 patients were studied. Analysis was performed using the statistical software Review Manager Version 4.2. The data available show that laparoscopic myomectomy was associated with less hemoglobin drop, reduced operative blood loss, more patients fully recuperated at day 15, diminished postoperative pain, and fewer overall complications but longer operation time. However, major complications, pregnancy and recurrence were comparable in the two groups. The data show that if performed by suitably specialized surgeons in selected patients, laparoscopic myomectomy is a better choice than open surgery.
ISSN:0301-2115
1872-7654
DOI:10.1016/j.ejogrb.2009.03.009