Parathyroid carcinoma: clinical presentation and management

Abstract Parathyroid carcinoma constitutes a rare cause of hyperparathyroidism. Five patients, presenting with symptoms and clinical signs of parathyroid hyperfunction, were diagnosed with parathyroid carcinoma in our department over a 12-year period. The experience we gained in the management of th...

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Bibliographic Details
Published in:American journal of otolaryngology 2009-07, Vol.30 (4), p.277-280
Main Authors: Schoretsanitis, George, MD, Daskalakis, Markos, MD, Melissas, John, MD, Tsiftsis, Dimitris D., MD, PhD
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Biopsy
Diagnosis, Differential
Endocrinopathies
Female
Follow-Up Studies
Humans
Male
Malignant tumors
Medical sciences
Middle Aged
Otolaryngology
Otorhinolaryngology. Stomatology
Parathyroid Neoplasms - diagnosis
Parathyroid Neoplasms - surgery
Parathyroidectomy - methods
Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases)
Surgery
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed
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Summary:Abstract Parathyroid carcinoma constitutes a rare cause of hyperparathyroidism. Five patients, presenting with symptoms and clinical signs of parathyroid hyperfunction, were diagnosed with parathyroid carcinoma in our department over a 12-year period. The experience we gained in the management of these tumors is presented. The aim of this study is to elucidate the clinical features of the disease, the surgical treatment, and the sensitivity of the imaging modalities used to enhance the diagnostic ability. Preoperative recognition and intraoperative identification of this rare endocrine malignancy require a high index of clinical suspicion. Intraoperative awareness is needed of the malignant potential of the encountered lesion.
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2008.05.006