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Parathyroid carcinoma: clinical presentation and management

Abstract Parathyroid carcinoma constitutes a rare cause of hyperparathyroidism. Five patients, presenting with symptoms and clinical signs of parathyroid hyperfunction, were diagnosed with parathyroid carcinoma in our department over a 12-year period. The experience we gained in the management of th...

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Published in:	American journal of otolaryngology 2009-07, Vol.30 (4), p.277-280
Main Authors:	Schoretsanitis, George, MD, Daskalakis, Markos, MD, Melissas, John, MD, Tsiftsis, Dimitris D., MD, PhD
Format:	Article
Language:	English
Subjects:	Aged Biological and medical sciences Biopsy Diagnosis, Differential Endocrinopathies Female Follow-Up Studies Humans Male Malignant tumors Medical sciences Middle Aged Otolaryngology Otorhinolaryngology. Stomatology Parathyroid Neoplasms - diagnosis Parathyroid Neoplasms - surgery Parathyroidectomy - methods Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases) Surgery Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed
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creator	Schoretsanitis, George, MD Daskalakis, Markos, MD Melissas, John, MD Tsiftsis, Dimitris D., MD, PhD
description	Abstract Parathyroid carcinoma constitutes a rare cause of hyperparathyroidism. Five patients, presenting with symptoms and clinical signs of parathyroid hyperfunction, were diagnosed with parathyroid carcinoma in our department over a 12-year period. The experience we gained in the management of these tumors is presented. The aim of this study is to elucidate the clinical features of the disease, the surgical treatment, and the sensitivity of the imaging modalities used to enhance the diagnostic ability. Preoperative recognition and intraoperative identification of this rare endocrine malignancy require a high index of clinical suspicion. Intraoperative awareness is needed of the malignant potential of the encountered lesion.
doi_str_mv	10.1016/j.amjoto.2008.05.006
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Five patients, presenting with symptoms and clinical signs of parathyroid hyperfunction, were diagnosed with parathyroid carcinoma in our department over a 12-year period. The experience we gained in the management of these tumors is presented. The aim of this study is to elucidate the clinical features of the disease, the surgical treatment, and the sensitivity of the imaging modalities used to enhance the diagnostic ability. Preoperative recognition and intraoperative identification of this rare endocrine malignancy require a high index of clinical suspicion. 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subjects	Aged Biological and medical sciences Biopsy Diagnosis, Differential Endocrinopathies Female Follow-Up Studies Humans Male Malignant tumors Medical sciences Middle Aged Otolaryngology Otorhinolaryngology. Stomatology Parathyroid Neoplasms - diagnosis Parathyroid Neoplasms - surgery Parathyroidectomy - methods Parathyroids. Parafollicular cells. Cholecalciferol. Phosphocalcic homeostasis (diseases) Surgery Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed
title	Parathyroid carcinoma: clinical presentation and management
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