Thyrotoxicosis—an uncommon cause of heart failure

A 26-year-old man presented with high output heart failure and severe systolic left ventricular dysfunction. The underlying cause was determined to be thyrotoxicosis. With aggressive treatment of the hyperthyroid state, near-normalization of the patient's left ventricular systolic function was...

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Bibliographic Details
Published in:Cardiovascular pathology 2005, Vol.14 (1), p.24-27
Main Authors: Froeschl, Michael, Haddad, Haissam, Commons, A. Susan, Veinot, John P.
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - therapeutic use
Adult
Antithyroid Agents - therapeutic use
Congestive heart failure
Drug Therapy, Combination
Echocardiography
Fatal Outcome
Goiter
Heart
Heart Failure - etiology
Heart Failure - pathology
Humans
Hydrocortisone - therapeutic use
Hyperplasia
Hyperthyroidism - complications
Hyperthyroidism - pathology
Hyperthyroidism - therapy
Iodides - pharmacology
Male
Methimazole - therapeutic use
Mortality
Regional Blood Flow - drug effects
Systole
Thyroid
Thyroid Gland - blood supply
Thyrotoxicosis - complications
Thyrotoxicosis - pathology
Thyrotoxicosis - therapy
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - pathology
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Summary:A 26-year-old man presented with high output heart failure and severe systolic left ventricular dysfunction. The underlying cause was determined to be thyrotoxicosis. With aggressive treatment of the hyperthyroid state, near-normalization of the patient's left ventricular systolic function was achieved. Unfortunately, he succumbed to pancreatitis, followed by multiple ICU complications. A brief review of the literature is provided.
ISSN:1054-8807
1879-1336
DOI:10.1016/j.carpath.2004.11.003