Ligamentous versus physeal failure in murine medial collateral ligament biomechanical testing

This study examines the age at which a femoral physeal failure ceased to occur in a mouse model of medial collateral ligament (MCL) testing. Biomechanical testing of the MCL with load to failure can result in physeal failure rather than MCL failure in skeletally immature animals. Failure mode depend...

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Bibliographic Details
Published in:Journal of biomechanics 2005-04, Vol.38 (4), p.703-706
Main Authors: El-Zawawy, H.B., Silva, M.J., Sandell, L.J., Wright, R.W.
Format: Article
Language:English
Subjects:
Age
Age Factors
Animals
Biomechanical Phenomena
Biomechanics
Bones
Cartilage
Epiphyses - injuries
Epiphyses - physiopathology
Failure
Femur
Handedness
Knee
Ligaments
Ligaments - injuries
Ligaments - physiopathology
Male
MCL
Medial Collateral Ligament, Knee - diagnostic imaging
Medial Collateral Ligament, Knee - injuries
Medial Collateral Ligament, Knee - physiology
Mice
Mice, Inbred Strains
Murine
Physis
Radiography
Variance analysis
Weight-Bearing
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Summary:This study examines the age at which a femoral physeal failure ceased to occur in a mouse model of medial collateral ligament (MCL) testing. Biomechanical testing of the MCL with load to failure can result in physeal failure rather than MCL failure in skeletally immature animals. Failure mode depended significantly on age ( p
ISSN:0021-9290
1873-2380
DOI:10.1016/j.jbiomech.2004.05.014