Multipoint viscosity measurements in microfluidic channels using optical tweezers

We demonstrate the technique of multipoint viscosity measurements incorporating the accurate calibration of micron sized particles. We describe the use of a high-speed camera to measure the residual motion of particles trapped in holographic optical tweezers, enabling us to calculate the fluid visco...

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Bibliographic Details
Published in:Lab on a chip 2009-01, Vol.9 (14), p.2059-2062
Main Authors: Keen, Stephen, Yao, Alison, Leach, Jonathan, Di Leonardo, Roberto, Saunter, Chris, Love, Gordon, Cooper, Jonathan, Padgett, Miles
Format: Article
Language:English
Subjects:
Calibration
Microfluidic Analytical Techniques
Microscopy
Microspheres
Motion
Optical Tweezers
Photography
Silicon Dioxide - chemistry
Viscosity
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Summary:We demonstrate the technique of multipoint viscosity measurements incorporating the accurate calibration of micron sized particles. We describe the use of a high-speed camera to measure the residual motion of particles trapped in holographic optical tweezers, enabling us to calculate the fluid viscosity at multiple points across the field-of-view of the microscope within a microfluidic system.
ISSN:1473-0197
1473-0189
DOI:10.1039/b900934e