Effect of cirrhosis and liver transplantation on the gender difference in QT interval

The effect of gender on the QT interval in patients with cirrhosis before and after liver transplantation and the relation between the QT interval and changes in gender hormones after liver transplantation were assessed. The study showed that (1) physiologic gender difference in the QTc interval is...

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Bibliographic Details
Published in:The American journal of cardiology 2005-03, Vol.95 (5), p.691-694
Main Authors: Adigun, Adegboyega Q., Pinto, Amar G., Flockhart, David A., Gorski, J. Christopher, Li, Lang, Hall, Stephen D., Chalasani, Naga
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Cardiology. Vascular system
Electrocardiography
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Liver Cirrhosis - complications
Liver Cirrhosis - surgery
Liver Transplantation
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Long QT Syndrome - complications
Long QT Syndrome - physiopathology
Male
Medical sciences
Middle Aged
Other diseases. Semiology
Sex Factors
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Summary:The effect of gender on the QT interval in patients with cirrhosis before and after liver transplantation and the relation between the QT interval and changes in gender hormones after liver transplantation were assessed. The study showed that (1) physiologic gender difference in the QTc interval is abolished in cirrhosis, and it is not restored after liver transplantation, and (2) gender hormone concentrations had no effect on the QTc interval.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.10.054