Sudden re-opening of collapsed transverse sinuses and longstanding clinical remission after a single lumbar puncture in a case of idiopathic intracranial hypertension. Pathogenetic implications

The aetiopathogenetic role of sinus venous obstructions carried by most idiopathic intracranial hypertension (IIH) patients is controversial. We report the case of a young woman diagnosed with IIH with papilloedema and narrowing of transverse sinuses, in which lowering of intracranial pressure by a...

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Bibliographic Details
Published in:Neurological sciences 2005-02, Vol.25 (6), p.342-344
Main Authors: De Simone, R, Marano, E, Fiorillo, C, Briganti, F, Di Salle, F, Volpe, A, Bonavita, V
Format: Article
Language:English
Subjects:
Adult
Cranial Sinuses - diagnostic imaging
Cranial Sinuses - pathology
Female
Humans
Pseudotumor Cerebri - therapy
Radiography
Remission Induction
Spinal Puncture - methods
Time
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Summary:The aetiopathogenetic role of sinus venous obstructions carried by most idiopathic intracranial hypertension (IIH) patients is controversial. We report the case of a young woman diagnosed with IIH with papilloedema and narrowing of transverse sinuses, in which lowering of intracranial pressure by a single 20 ml cerebrospinal fluid (CSF) resulted in a strong dimensional increase of the transverse sinuses. Changes were followed by clinical remission and normalisation of optical nerve calibre, maintained after a 2-month follow-up. Our findings indicate that, although secondary to CSF hypertension, venous sinuses compression may have an important role in hypertensive status maintenance. Pathogenetic implications of venous sinus compression by hypertensive CSF in IIH are discussed.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-004-0368-3