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In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain
The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at b...
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Published in: | European radiology 2009-08, Vol.19 (8), p.2049-2059 |
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creator | Majós, Carles Aguilera, Carles Cos, Mònica Camins, Àngels Candiota, Ana P. Delgado-Goñi, Teresa Samitier, Àlex Castañer, Sara Sánchez, Juan J. Mato, David Acebes, Juan J. Arús, Carles |
description | The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p |
doi_str_mv | 10.1007/s00330-009-1357-y |
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Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p < 0.001 and p < 0.01, respectively), high mobile lipids in metastasis (p < 0.001), high Cho in PNET (p < 0.001), high mI + Gly in ependymoma (p < 0.001), high NAC (p < 0.01) in the absence of the normal brain parenchyma pattern in colloid cysts, and high mI/Gly and Ala in central neurocytoma. Proton MR spectroscopy provides additional metabolic information that could be useful in the diagnosis of intraventricular brain tumors.]]></description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-009-1357-y</identifier><identifier>PMID: 19277673</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adolescent ; Adult ; Aged ; Biomarkers, Tumor - analysis ; Brain - metabolism ; Brain cancer ; Cerebral Ventricle Neoplasms - diagnosis ; Cerebral Ventricle Neoplasms - metabolism ; Clinical medicine ; Diagnostic Radiology ; Female ; Histology ; Humans ; Imaging ; Internal Medicine ; Interventional Radiology ; Male ; Medicine ; Medicine & Public Health ; Metastasis ; Middle Aged ; Neuro ; Neuroradiology ; Protons ; Radiology ; Reproducibility of Results ; Sensitivity and Specificity ; Spectrum analysis ; Statistical analysis ; Tumors ; Ultrasound ; Young Adult</subject><ispartof>European radiology, 2009-08, Vol.19 (8), p.2049-2059</ispartof><rights>European Society of Radiology 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-ea6c3d6fd180145c778b8b81dfa932fc4727a14b3bd7fe7c243cf90bfd51a1cf3</citedby><cites>FETCH-LOGICAL-c400t-ea6c3d6fd180145c778b8b81dfa932fc4727a14b3bd7fe7c243cf90bfd51a1cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19277673$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Majós, Carles</creatorcontrib><creatorcontrib>Aguilera, Carles</creatorcontrib><creatorcontrib>Cos, Mònica</creatorcontrib><creatorcontrib>Camins, Àngels</creatorcontrib><creatorcontrib>Candiota, Ana P.</creatorcontrib><creatorcontrib>Delgado-Goñi, Teresa</creatorcontrib><creatorcontrib>Samitier, Àlex</creatorcontrib><creatorcontrib>Castañer, Sara</creatorcontrib><creatorcontrib>Sánchez, Juan J.</creatorcontrib><creatorcontrib>Mato, David</creatorcontrib><creatorcontrib>Acebes, Juan J.</creatorcontrib><creatorcontrib>Arús, Carles</creatorcontrib><title>In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description><![CDATA[The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p < 0.001 and p < 0.01, respectively), high mobile lipids in metastasis (p < 0.001), high Cho in PNET (p < 0.001), high mI + Gly in ependymoma (p < 0.001), high NAC (p < 0.01) in the absence of the normal brain parenchyma pattern in colloid cysts, and high mI/Gly and Ala in central neurocytoma. Proton MR spectroscopy provides additional metabolic information that could be useful in the diagnosis of intraventricular brain tumors.]]></description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Biomarkers, Tumor - analysis</subject><subject>Brain - metabolism</subject><subject>Brain cancer</subject><subject>Cerebral Ventricle Neoplasms - diagnosis</subject><subject>Cerebral Ventricle Neoplasms - metabolism</subject><subject>Clinical medicine</subject><subject>Diagnostic Radiology</subject><subject>Female</subject><subject>Histology</subject><subject>Humans</subject><subject>Imaging</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Neuro</subject><subject>Neuroradiology</subject><subject>Protons</subject><subject>Radiology</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Spectrum analysis</subject><subject>Statistical analysis</subject><subject>Tumors</subject><subject>Ultrasound</subject><subject>Young Adult</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNqFkUtLAzEUhYMotlZ_gBsJLtyN3jw6mVlK8VEouFFchkwmqVM6SU1mCvPvTWmhIIgEksX97rm55yB0TeCeAIiHCMAYZABlRthUZMMJGhPOaEag4KdoDCUrMlGWfIQuYlxBAgkX52hESipELtgYfc4d3jZbjzfBd97hVi2d6RqNg4neKacNjhuju-Cj9psBe4sb1wW1NeludL9WAXd96_sQd7Xuy-AqqMZdojOr1tFcHd4J-nh-ep-9Zou3l_nscZFpDtBlRuWa1bmtSQGET7UQRZUOqa0qGbWaCyoU4RWramGN0JQzbUuobD0limjLJuhur5v-_92b2Mm2idqs18oZ30eZCz4toGD_gpRQmlNWJvD2F7hK27m0RGKKZBzlRYLIHtLJmBiMlZvQtCoMkoDcZSP32chkudxlI4fUc3MQ7qvW1MeOQxgJoHsgppJbmnCc_LfqDxn2m6A</recordid><startdate>20090801</startdate><enddate>20090801</enddate><creator>Majós, Carles</creator><creator>Aguilera, Carles</creator><creator>Cos, Mònica</creator><creator>Camins, Àngels</creator><creator>Candiota, Ana P.</creator><creator>Delgado-Goñi, Teresa</creator><creator>Samitier, Àlex</creator><creator>Castañer, Sara</creator><creator>Sánchez, Juan J.</creator><creator>Mato, David</creator><creator>Acebes, Juan J.</creator><creator>Arús, Carles</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20090801</creationdate><title>In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain</title><author>Majós, Carles ; Aguilera, Carles ; Cos, Mònica ; Camins, Àngels ; Candiota, Ana P. ; Delgado-Goñi, Teresa ; Samitier, Àlex ; Castañer, Sara ; Sánchez, Juan J. ; Mato, David ; Acebes, Juan J. ; Arús, Carles</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-ea6c3d6fd180145c778b8b81dfa932fc4727a14b3bd7fe7c243cf90bfd51a1cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Biomarkers, Tumor - 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Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Majós, Carles</au><au>Aguilera, Carles</au><au>Cos, Mònica</au><au>Camins, Àngels</au><au>Candiota, Ana P.</au><au>Delgado-Goñi, Teresa</au><au>Samitier, Àlex</au><au>Castañer, Sara</au><au>Sánchez, Juan J.</au><au>Mato, David</au><au>Acebes, Juan J.</au><au>Arús, Carles</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2009-08-01</date><risdate>2009</risdate><volume>19</volume><issue>8</issue><spage>2049</spage><epage>2059</epage><pages>2049-2059</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract><![CDATA[The aim of this study was to assess the usefulness of proton MR spectroscopy in the diagnosis of intraventricular tumours. Fifty-two intraventricular tumours pertaining to 16 different tumour types were derived from our database. All cases had single-voxel proton MR spectroscopy performed at TE at both 30 and 136 ms at 1.5 T. The Mann-Whitney U test was used to search for the most discriminative datapoints each tumour type. Characteristic trends were found for some groups: high Glx and Ala in meningiomas (p < 0.001 and p < 0.01, respectively), high mobile lipids in metastasis (p < 0.001), high Cho in PNET (p < 0.001), high mI + Gly in ependymoma (p < 0.001), high NAC (p < 0.01) in the absence of the normal brain parenchyma pattern in colloid cysts, and high mI/Gly and Ala in central neurocytoma. Proton MR spectroscopy provides additional metabolic information that could be useful in the diagnosis of intraventricular brain tumors.]]></abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>19277673</pmid><doi>10.1007/s00330-009-1357-y</doi><tpages>11</tpages></addata></record> |
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subjects | Adolescent Adult Aged Biomarkers, Tumor - analysis Brain - metabolism Brain cancer Cerebral Ventricle Neoplasms - diagnosis Cerebral Ventricle Neoplasms - metabolism Clinical medicine Diagnostic Radiology Female Histology Humans Imaging Internal Medicine Interventional Radiology Male Medicine Medicine & Public Health Metastasis Middle Aged Neuro Neuroradiology Protons Radiology Reproducibility of Results Sensitivity and Specificity Spectrum analysis Statistical analysis Tumors Ultrasound Young Adult |
title | In vivo proton magnetic resonance spectroscopy of intraventricular tumours of the brain |
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