Asymptomatic Left Ventricular Systolic Dysfunction in Essential Hypertension: Prevalence, Determinants, and Prognostic Value

Prevalence, determinants, and prognostic value of asymptomatic left ventricular systolic dysfunction (LVSD) in uncomplicated subjects with essential hypertension are still incompletely known. We studied 2384 initially untreated subjects with hypertension, no previous cardiovascular disease, and no s...

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Bibliographic Details
Published in:Hypertension (Dallas, Tex. 1979) Tex. 1979), 2005-03, Vol.45 (3), p.412-418
Main Authors: Verdecchia, Paolo, Angeli, Fabio, Gattobigio, Roberto, Sardone, Mariagrazia, Porcellati, Carlo
Format: Article
Language:English
Subjects:
Adult
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure Monitoring, Ambulatory
Cardiology. Vascular system
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Echocardiography
Electrocardiography
Experimental diseases
Female
Humans
Hypertension - complications
Hypertrophy, Left Ventricular - complications
Incidence
Longitudinal Studies
Male
Medical sciences
Middle Aged
Multivariate Analysis
Prevalence
Prognosis
Proportional Hazards Models
Smoking - adverse effects
Systole
Ventricular Dysfunction, Left - diagnosis
Ventricular Dysfunction, Left - epidemiology
Ventricular Dysfunction, Left - physiopathology
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Summary:Prevalence, determinants, and prognostic value of asymptomatic left ventricular systolic dysfunction (LVSD) in uncomplicated subjects with essential hypertension are still incompletely known. We studied 2384 initially untreated subjects with hypertension, no previous cardiovascular disease, and no symptoms or physical signs of congestive heart failure (CHF). These subjects were studied at entry and followed for up to 17 years (mean 6.0). Asymptomatic LVSD (ALVSD), defined by an echocardiographic ejection fraction
ISSN:0194-911X
1524-4563
DOI:10.1161/01.HYP.0000154822.37141.f6