Node-by-node correlation between MR and PET/CT in patients with uterine cervical cancer: diffusion-weighted imaging versus size-based criteria on T2WI

• Published in: European radiology 2009-08, Vol.19 (8), p.2024-2032
• Main Authors: Choi, Eugene K., Kim, Jeong Kon, Choi, Hyuck Jae, Park, Seong Ho, Park, Bum-Woo, Kim, Namkug, Kim, Jae Seung, Im, Ki Chun, Cho, Gyunggoo, Cho, Kyoung-Sik
• Format: Article
• Language: English
• Subjects: Cervical cancer; Diagnostic Radiology; Diffusion Magnetic Resonance Imaging - methods; Female; Humans; Imaging; Internal Medicine; Interventional Radiology; Lymph Nodes - diagnostic imaging; Lymph Nodes - pathology; Lymphatic Metastasis; Magnetic Resonance; Magnetic Resonance Imaging - methods; Medicine; Medicine & Public Health; Middle Aged; Neuroradiology; Positron-Emission Tomography; Radiology; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Tomography, X-Ray Computed; Ultrasound
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s00330-009-1350-5

The purpose of the study was to perform a node-by-node comparison of an ADC-based diagnosis and various size-based criteria on T2-weighted imaging (T2WI) with regard to their correlation with PET/CT findings in patients with uterine cervical cancer. In 163 patients with 339 pelvic lymph nodes (LNs) with short-axis diameter >5 mm, the minimum apparent diffusion coefficient (ADC), mean ADC, short- and long-axis diameters, and ratio of long- to short-axis diameters (L/S ratio) were compared in PET/CT-positive and -negative LNs. On PET/CT, 118 (35%) LNs in 58 patients were positive. The mean value of minimum and mean ADCs, short- and long-axis diameters, and L/S ratio were different in PET/CT-positive (0.6436 × 10 −3 mm 2 /s, 0.756 × 10 −3 mm 2 /s, 10.3 mm, 13.2 mm, 1.32, respectively) and PET/CT-negative LNs (0.8893 × 10 −3 mm 2 /s, 1.019 × 10 −3 mm 2 /s, 7.4 mm, 11.0 mm, 1.49, respectively) ( P