Benign Hürthle Cell Adenoma with Papillary Architecture: A Benign Lesion Mimicking Oncocytic Papillary Carcinoma

We studied the significance of encapsulated Hürthle cell thyroid nodules with papillary structures lacking the nuclear features of papillary thyroid carcinoma (PTC); 19 cases fulfilling these criteria were encountered The patients' ages ranged from 22 to 40 years (32±6), and the F:M ratio was 3...

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Bibliographic Details
Published in:International journal of surgical pathology 2005-01, Vol.13 (1), p.37-41
Main Authors: Mai, Kien T., Elmontaser, Ghazi, Perkins, D. Garth, Thomas, Jane, Stinson, William A.
Format: Article
Language:English
Subjects:
Adenoma - chemistry
Adenoma - pathology
Adenoma - surgery
Adenoma, Oxyphilic - chemistry
Adenoma, Oxyphilic - pathology
Adenoma, Oxyphilic - surgery
Adult
Biomarkers, Tumor - analysis
Carcinoma, Papillary, Follicular - diagnosis
Chromatin - pathology
Diagnosis, Differential
Female
Humans
Male
Middle Aged
Thyroid Neoplasms - chemistry
Thyroid Neoplasms - pathology
Thyroid Neoplasms - surgery
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Summary:We studied the significance of encapsulated Hürthle cell thyroid nodules with papillary structures lacking the nuclear features of papillary thyroid carcinoma (PTC); 19 cases fulfilling these criteria were encountered The patients' ages ranged from 22 to 40 years (32±6), and the F:M ratio was 3:1 The tumors measured from 0.5-5 cm (2±1 .1). The diameter of the tumor cell nuclei ranged from 5.6 to 7.2 microns. Many nodules had nuclei displaying a fine chromatin pattern somewhat resembling those of PTC, but these were present in
ISSN:1066-8969
1940-2465
DOI:10.1177/106689690501300105