Effect of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Polymorphism Leu-214 on Replication Capacity and Drug Susceptibility

• Published in: Journal of Virology 2009-08, Vol.83 (15), p.7434-7439
• Main Authors: CARMEN PUERTAS, Maria, BUZON, Maria Jose, ARTESE, Anna, ALCARO, Stefano, MENENDEZ-ARIAS, Luis, FEDERICO PERNO, Carlo, CLOTET, Bonaventura, CECCHERINI-SILBERSTEIN, Francesca, MARTINEZ-PICADO, Javier
• Format: Article
• Language: English
• Subjects: Anti-HIV Agents - pharmacology; Biological and medical sciences; Cell Line; Drug Resistance, Viral; Fundamental and applied biological sciences. Psychology; HIV Infections - virology; HIV Reverse Transcriptase - genetics; HIV Reverse Transcriptase - metabolism; HIV-1 - drug effects; HIV-1 - enzymology; HIV-1 - genetics; HIV-1 - physiology; Human immunodeficiency virus 1; Humans; Leucine - genetics; Leucine - metabolism; Microbiology; Miscellaneous; Mutation; Polymorphism, Genetic; Vaccines and Antiviral Agents; Virology; Virus Replication - drug effects; Zidovudine - pharmacology
• ISSN: 0022-538X; 1098-5514; 1098-5514
• DOI: 10.1128/JVI.00487-09

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