The dual nature of homologous recombination in plants

Homologous recombination creates covalent linkages between DNA in regions of highly similar or identical sequence. Recent results from several laboratories, many of them based on forward and reverse genetics in Arabidopsis, give insights into the mechanisms of the enzymatic machinery and the involve...

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Bibliographic Details
Published in:Trends in genetics 2005-03, Vol.21 (3), p.172-181
Main Authors: Schuermann, David, Molinier, Jean, Fritsch, Olivier, Hohn, Barbara
Format: Article
Language:English
Subjects:
Arabidopsis
Arabidopsis - genetics
Arabidopsis thaliana
Biological and medical sciences
DNA Repair - physiology
Fundamental and applied biological sciences. Psychology
Genes, Plant - physiology
Genetics of eukaryotes. Biological and molecular evolution
homologous recombination
literature reviews
meiosis
Molecular and cellular biology
plant genetics
Recombination, Genetic
somatic recombination
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Summary:Homologous recombination creates covalent linkages between DNA in regions of highly similar or identical sequence. Recent results from several laboratories, many of them based on forward and reverse genetics in Arabidopsis, give insights into the mechanisms of the enzymatic machinery and the involvement of chromatin in somatic and meiotic DNA recombination. Also, signaling pathways and interconnections between repair pathways are being discovered. In addition, recent work shows that biotic and abiotic influences from the environment can dramatically affect plant genomes. The resulting changes in the DNA sequence, exerted at the level of somatic or meiotic tissue, might contribute to evolution.
ISSN:0168-9525
DOI:10.1016/j.tig.2005.01.002