Constipation in the Elderly: Management Strategies

• Published in: Drugs & aging 2009-01, Vol.26 (6), p.469-474
• Main Authors: Spinzi, Giancarlo, Amato, Arnaldo, Imperiali, Gianni, Lenoci, Nicoletta, Mandelli, Giovanna, Paggi, Silvia, Radaelli, Franco, Terreni, Natalia, Terruzzi, Vittorio
• Format: Article
• Language: English
• Subjects: Aged; Biological and medical sciences; Chronic Disease; Constipation; Constipation - diet therapy; Constipation - drug therapy; Constipation - therapy; Drug therapy; Evidence-Based Medicine; Exercise Therapy; Gastroenterology. Liver. Pancreas. Abdomen; Gastrointestinal Agents - therapeutic use; Geriatrics/Gerontology; Health aspects; Humans; Internal Medicine; Laxatives - therapeutic use; Medical sciences; Medicine; Medicine & Public Health; Methods; Other diseases. Semiology; Pharmacology. Drug treatments; Pharmacology/Toxicology; Pharmacotherapy; Prevalence studies (Epidemiology); Review Article; Risk factors; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
• ISSN: 1170-229X; 1179-1969
• DOI: 10.2165/00002512-200926060-00003

Constipation is a highly prevalent and bothersome disorder that negatively affects patients’ social and professional lives and places a great economic burden on both patients and national health services. An accurate determination of the prevalence of constipation is difficult because of the various definitions used, but many epidemiological studies have shown that it affects up to 20% of the population at any one time. Although constipation is not a physiological consequence of normal aging, decreased mobility and other co-morbid medical conditions may contribute to its prevalence in older adults. Functional constipation is diagnosed when no secondary causes can be identified. Patients have some unusual beliefs about their bowel habits. Systematic attention to history, examination and investigation, especially in older people, can be highly effective in resolving problems and in enhancing quality of life. There is a considerable range of treatment modalities available for patients with constipation, but the clinical evidence supporting their use varies widely. However, if constipation is not managed proactively, patients can experience negative consequences, such as anorexia, nausea, bowel impaction or bowel perforation. The clinical benefits of various traditional pharmacological and non-pharmacological agents remain unclear. The first steps in the treatment of simple constipation include increasing intake of dietary fibre and the use of a fibre supplement. Patients with severe constipation or those unable to comply with the recommended intake of fibre may benefit from the addition of laxatives. More recently, newer agents (e.g. tegaserod and lubiprostone), have been approved for the treatment of patients with chronic constipation. Additional work is needed to determine what role, if any, these agents may play in the treatment of patients with chronic constipation. The purpose of this review is to identify evidence-based interventions for the prevention and management of constipation in the elderly.