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Bilateral optic neuropathy and unilateral tonic pupil associated with acute human herpesvirus 6 infection: a case report

Human herpesvirus 6 (HHV-6), a widespread virus and causative agent of exanthema subitum in children, has been associated with a number of neurologic disorders including cranial nerve palsies, seizures, encephalitis, meningitis, and multiple sclerosis. A 31-year-old man presented with bilateral opti...

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Bibliographic Details
Published in:Graefe's archive for clinical and experimental ophthalmology 2005-02, Vol.243 (2), p.175-177
Main Authors: Oberacher-Velten, Isabel M, Jonas, Jost B, Jünemann, Anselm, Schmidt, Barbara
Format: Article
Language:English
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Summary:Human herpesvirus 6 (HHV-6), a widespread virus and causative agent of exanthema subitum in children, has been associated with a number of neurologic disorders including cranial nerve palsies, seizures, encephalitis, meningitis, and multiple sclerosis. A 31-year-old man presented with bilateral optic neuropathy, disc edema, and unilateral tonic pupil, which were found to be associated with acute HHV-6 infection. The patient had been suffering from juvenile diabetes for 5 years. One week after onset of intravenous antiviral therapy with foscarnet, disc edema subsided, and tonic pupil reaction was no longer detectable. HHV-6 infection may play a role as a causative agent in patients with optic neuropathy and tonic pupil.
ISSN:0721-832X
1435-702X
DOI:10.1007/s00417-004-0986-8