Spontaneous regression of a large hepatocellular carcinoma with skull metastasis

Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. This case of a 65‐year‐old Korean man with HCC and metastatic frontal bone mass that regressed after radiotherapy for frontal bone mass without any other therapeutic modalities is described. The clinical diagnosis of HCC...

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Bibliographic Details
Published in:Journal of gastroenterology and hepatology 2005-03, Vol.20 (3), p.488-492
Main Authors: NAM, SOON WOO, HAN, JOON‐YEOL, KIM, JIN IL, PARK, SOO HEON, CHO, SE HYUN, HAN, NAM IK, YANG, JIN MO, KIM, JAE KWANG, CHOI, SANG WOOK, LEE, YOUNG SUK, CHUNG, KYU WON, SUN, HEE SIK
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Biopsy
Carcinoma, Hepatocellular - pathology
Carcinoma, Hepatocellular - radiotherapy
Carcinoma, Hepatocellular - secondary
Follow-Up Studies
Frontal Bone - pathology
Frontal Bone - radiation effects
Gastroenterology. Liver. Pancreas. Abdomen
hepatocellular carcinoma
Humans
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - pathology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Neoplasm Regression, Spontaneous
Phellinus linteus
skull metastasis
Skull Neoplasms - pathology
Skull Neoplasms - radiotherapy
Skull Neoplasms - secondary
spontaneous regression
Time Factors
Tomography, X-Ray Computed
Tumors
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Summary:Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. This case of a 65‐year‐old Korean man with HCC and metastatic frontal bone mass that regressed after radiotherapy for frontal bone mass without any other therapeutic modalities is described. The clinical diagnosis of HCC was made because of the presence of a liver mass on abdominal computed tomography (CT) scan, high serum α‐fetoprotein value and tissue diagnosis on frontal bone biopsy. The patient refused any other recommended treatments, but accepted the radiation therapy due to a painful frontal bone mass, and ingested mushroom called Phellinus linteus for one and a half years. Ten months after radiation therapy, he experienced a reduction in size of the frontal bone mass and improvement of lesions in the liver, sternum and ribs. The patient is alive and in good condition without any symptoms or tumor aggravation in August 2002. It was concluded that a rare case of spontaneous regression of HCC had occurred.
ISSN:0815-9319
1440-1746
DOI:10.1111/j.1440-1746.2005.03243.x