Loading…

Preimplantation genetic diagnosis to prevent disorders in children

Preimplantation genetic diagnosis (PGD) is an alternative reproductive option for couples at risk of having a child affected with a genetic disorder. Although prenatal diagnosis (PND) has been available for many years, it is not acceptable to many owing to issues relating to termination of pregnancy...

Full description

Saved in:

Bibliographic Details
Published in:	British journal of nursing (Mark Allen Publishing) 2005, Vol.14 (2), p.64-70
Main Author:	Lashwood, Alison
Format:	Article
Language:	English
Subjects:	Bioethics Female Genetic Counseling Genetic Diseases, Inborn - prevention & control Humans Nursing Preconception Care Pregnancy Pregnancy Outcome Reproductive Techniques, Assisted
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by
cites
container_end_page	70
container_issue	2
container_start_page	64
container_title	British journal of nursing (Mark Allen Publishing)
container_volume	14
creator	Lashwood, Alison
description	Preimplantation genetic diagnosis (PGD) is an alternative reproductive option for couples at risk of having a child affected with a genetic disorder. Although prenatal diagnosis (PND) has been available for many years, it is not acceptable to many owing to issues relating to termination of pregnancy. PGD involves assisted-reproductive technology, even though most couples undertaking it are fertile. However, if the treatment is successful, the couple will not have to consider PND. PGD is only available at a small number of centres and for a limited number of genetic conditions. It is a complex and time-consuming procedure. The success rate is around 20%, consequently, there is a relatively low chance of success and this requires careful consideration by couples who generally can become spontaneously pregnant. However, PGD is now more widely understood and available to all at the point of referral. This article sets out to explain the PGD procedure, its implications, limitations, and regulation in the UK and to discuss associated dilemmas.
doi_str_mv	10.12968/bjon.2005.14.2.17433
format	article
fullrecord	<record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_67485816</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67485816</sourcerecordid><originalsourceid>FETCH-LOGICAL-p124t-4a5b435b724c21c5ec91ddab6c1d176f6a73e17cdb5feb662a47263fd94dfa0f3</originalsourceid><addsrcrecordid>eNo1j0tLxDAcxHNQ3HX1Iyg9eWvNO9ujLr5gQQ96Lnn8u2Zpk5pkBb-9BVfmMDD8GGYQuiK4IbSV61uzj6GhGIuG8IY2RHHGTtASt1LWmEuyQOc57zHGEnNyhhZEKIFnLdH9WwI_ToMORRcfQ7WDAMXbynm9CzH7XJVYTQm-IZQ5zDE5SLnyobKffnAJwgU67fWQ4fLoK_Tx-PC-ea63r08vm7ttPRHKS821MJwJoyi3lFgBtiXOaSMtcUTJXmrFgCjrjOjBSEk1V1Sy3rXc9Rr3bIVu_nqnFL8OkEs3-mxhmLdDPOROKr4WayJn8PoIHswIrpuSH3X66f5fs18KcVqJ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67485816</pqid></control><display><type>article</type><title>Preimplantation genetic diagnosis to prevent disorders in children</title><source>Social Science Premium Collection (Proquest) (PQ_SDU_P3)</source><source>Sociology Collection</source><creator>Lashwood, Alison</creator><creatorcontrib>Lashwood, Alison</creatorcontrib><description>Preimplantation genetic diagnosis (PGD) is an alternative reproductive option for couples at risk of having a child affected with a genetic disorder. Although prenatal diagnosis (PND) has been available for many years, it is not acceptable to many owing to issues relating to termination of pregnancy. PGD involves assisted-reproductive technology, even though most couples undertaking it are fertile. However, if the treatment is successful, the couple will not have to consider PND. PGD is only available at a small number of centres and for a limited number of genetic conditions. It is a complex and time-consuming procedure. The success rate is around 20%, consequently, there is a relatively low chance of success and this requires careful consideration by couples who generally can become spontaneously pregnant. However, PGD is now more widely understood and available to all at the point of referral. This article sets out to explain the PGD procedure, its implications, limitations, and regulation in the UK and to discuss associated dilemmas.</description><identifier>ISSN: 0966-0461</identifier><identifier>DOI: 10.12968/bjon.2005.14.2.17433</identifier><identifier>PMID: 15750505</identifier><language>eng</language><publisher>England</publisher><subject>Bioethics ; Female ; Genetic Counseling ; Genetic Diseases, Inborn - prevention & control ; Humans ; Nursing ; Preconception Care ; Pregnancy ; Pregnancy Outcome ; Reproductive Techniques, Assisted</subject><ispartof>British journal of nursing (Mark Allen Publishing), 2005, Vol.14 (2), p.64-70</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925,33612,34531</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15750505$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lashwood, Alison</creatorcontrib><title>Preimplantation genetic diagnosis to prevent disorders in children</title><title>British journal of nursing (Mark Allen Publishing)</title><addtitle>Br J Nurs</addtitle><description>Preimplantation genetic diagnosis (PGD) is an alternative reproductive option for couples at risk of having a child affected with a genetic disorder. Although prenatal diagnosis (PND) has been available for many years, it is not acceptable to many owing to issues relating to termination of pregnancy. PGD involves assisted-reproductive technology, even though most couples undertaking it are fertile. However, if the treatment is successful, the couple will not have to consider PND. PGD is only available at a small number of centres and for a limited number of genetic conditions. It is a complex and time-consuming procedure. The success rate is around 20%, consequently, there is a relatively low chance of success and this requires careful consideration by couples who generally can become spontaneously pregnant. However, PGD is now more widely understood and available to all at the point of referral. This article sets out to explain the PGD procedure, its implications, limitations, and regulation in the UK and to discuss associated dilemmas.</description><subject>Bioethics</subject><subject>Female</subject><subject>Genetic Counseling</subject><subject>Genetic Diseases, Inborn - prevention & control</subject><subject>Humans</subject><subject>Nursing</subject><subject>Preconception Care</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Reproductive Techniques, Assisted</subject><issn>0966-0461</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><recordid>eNo1j0tLxDAcxHNQ3HX1Iyg9eWvNO9ujLr5gQQ96Lnn8u2Zpk5pkBb-9BVfmMDD8GGYQuiK4IbSV61uzj6GhGIuG8IY2RHHGTtASt1LWmEuyQOc57zHGEnNyhhZEKIFnLdH9WwI_ToMORRcfQ7WDAMXbynm9CzH7XJVYTQm-IZQ5zDE5SLnyobKffnAJwgU67fWQ4fLoK_Tx-PC-ea63r08vm7ttPRHKS821MJwJoyi3lFgBtiXOaSMtcUTJXmrFgCjrjOjBSEk1V1Sy3rXc9Rr3bIVu_nqnFL8OkEs3-mxhmLdDPOROKr4WayJn8PoIHswIrpuSH3X66f5fs18KcVqJ</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Lashwood, Alison</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2005</creationdate><title>Preimplantation genetic diagnosis to prevent disorders in children</title><author>Lashwood, Alison</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p124t-4a5b435b724c21c5ec91ddab6c1d176f6a73e17cdb5feb662a47263fd94dfa0f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Bioethics</topic><topic>Female</topic><topic>Genetic Counseling</topic><topic>Genetic Diseases, Inborn - prevention & control</topic><topic>Humans</topic><topic>Nursing</topic><topic>Preconception Care</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Reproductive Techniques, Assisted</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lashwood, Alison</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of nursing (Mark Allen Publishing)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lashwood, Alison</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preimplantation genetic diagnosis to prevent disorders in children</atitle><jtitle>British journal of nursing (Mark Allen Publishing)</jtitle><addtitle>Br J Nurs</addtitle><date>2005</date><risdate>2005</risdate><volume>14</volume><issue>2</issue><spage>64</spage><epage>70</epage><pages>64-70</pages><issn>0966-0461</issn><abstract>Preimplantation genetic diagnosis (PGD) is an alternative reproductive option for couples at risk of having a child affected with a genetic disorder. Although prenatal diagnosis (PND) has been available for many years, it is not acceptable to many owing to issues relating to termination of pregnancy. PGD involves assisted-reproductive technology, even though most couples undertaking it are fertile. However, if the treatment is successful, the couple will not have to consider PND. PGD is only available at a small number of centres and for a limited number of genetic conditions. It is a complex and time-consuming procedure. The success rate is around 20%, consequently, there is a relatively low chance of success and this requires careful consideration by couples who generally can become spontaneously pregnant. However, PGD is now more widely understood and available to all at the point of referral. This article sets out to explain the PGD procedure, its implications, limitations, and regulation in the UK and to discuss associated dilemmas.</abstract><cop>England</cop><pmid>15750505</pmid><doi>10.12968/bjon.2005.14.2.17433</doi><tpages>7</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0966-0461
ispartof	British journal of nursing (Mark Allen Publishing), 2005, Vol.14 (2), p.64-70
issn	0966-0461
language	eng
recordid	cdi_proquest_miscellaneous_67485816
source	Social Science Premium Collection (Proquest) (PQ_SDU_P3); Sociology Collection
subjects	Bioethics Female Genetic Counseling Genetic Diseases, Inborn - prevention & control Humans Nursing Preconception Care Pregnancy Pregnancy Outcome Reproductive Techniques, Assisted
title	Preimplantation genetic diagnosis to prevent disorders in children
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T14%3A47%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preimplantation%20genetic%20diagnosis%20to%20prevent%20disorders%20in%20children&rft.jtitle=British%20journal%20of%20nursing%20(Mark%20Allen%20Publishing)&rft.au=Lashwood,%20Alison&rft.date=2005&rft.volume=14&rft.issue=2&rft.spage=64&rft.epage=70&rft.pages=64-70&rft.issn=0966-0461&rft_id=info:doi/10.12968/bjon.2005.14.2.17433&rft_dat=%3Cproquest_pubme%3E67485816%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-p124t-4a5b435b724c21c5ec91ddab6c1d176f6a73e17cdb5feb662a47263fd94dfa0f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=67485816&rft_id=info:pmid/15750505&rfr_iscdi=true