Calculating the exclusion probability and paternity index for X-chromosomal loci in the presence of substructure

There has been recent interest in the use of X-chromosomal loci for forensic and relatedness testing casework, with many authors developing new X-linked short tandem repeat (STR) loci suitable for forensic use. Here we present formulae for two key quantities in paternity testing, the average probabi...

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Bibliographic Details
Published in:Forensic science international 2005-05, Vol.149 (2), p.201-203
Main Authors: Ayres, Karen L., Powley, William M.
Format: Article
Language:English
Subjects:
Alleles
Animal populations
Biological and medical sciences
Chromosomes, Human, X
Combinatorial probabilities
DNA Fingerprinting - methods
F ST
Female
Forensic sciences
General aspects
Genomics
Geometric probabilities
Humans
Investigative techniques, diagnostic techniques (general aspects)
Likelihood Functions
Male
Medical sciences
Mutation
Paternity
Paternity testing
Probabilities
Probability
Subpopulation
X chromosome
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Summary:There has been recent interest in the use of X-chromosomal loci for forensic and relatedness testing casework, with many authors developing new X-linked short tandem repeat (STR) loci suitable for forensic use. Here we present formulae for two key quantities in paternity testing, the average probability of exclusion and the paternity index, which are suitable for X-chromosomal loci in the presence of population substructure.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2004.06.017