Preventing stroke in people with atrial fibrillation: a cross-sectional study

• Published in: Journal of public health (Oxford, England) England), 2005-03, Vol.27 (1), p.85-92
• Main Authors: de Lusignan, Simon, Van Vlymen, Jeremy, Hague, Nigel, Thana, Lavanya, Dzregah, Billy, Chan, Tom
• Format: Article
• Language: English
• Subjects: Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants - administration & dosage; Anticoagulants - therapeutic use; Atrial fibrillation; Atrial Fibrillation - complications; Atrial Fibrillation - epidemiology; Cardiovascular Diseases - complications; Comorbidity; comparative study; Cross-Sectional Studies; Diabetes Complications - epidemiology; England; England - epidemiology; Family Practice - statistics & numerical data; Female; General practice; Health services; Humans; hypertension; Male; Middle Aged; Patients; Prevalence; Prevention; primary health care; Risk Assessment; Risk Factors; Sex Distribution; stroke; Stroke - epidemiology; Stroke - etiology; Stroke - prevention & control; Strokes; Wales - epidemiology; Warfarin - administration & dosage; Warfarin - therapeutic use
• ISSN: 1741-3842; 1741-3850
• DOI: 10.1093/pubmed/fdh201

Background The annual stroke rate in atrial fibrillation is around 5 per cent with increased risk in those with hypertension, diabetes, left ventricular dysfunction and other cardiovascular risk factors. This study set out to identify the patients with atrial fibrillation and modifiable risk factors for stroke. Method Analysis of practice computer data taken from eight general practices (81 811 patients) in the south of England. 944 patients with a diagnosis of atrial fibrillation, of whom 782 (82.8 per cent) were aged 65 years and over. Results The age standardised prevalence of diagnosed atrial fibrillation was 1.23 per cent (1.28 per cent for men and 1.18 per cent for women). It was much more prevalent in the older population, 8.28 per cent and 6.66 per cent for males and females over 65, respectively. Cardiovascular co-morbidities were more frequent with increasing age. Blood pressure (BP) was recorded in over 95 per cent of patients with atrial fibrillation though there was scope for improving control; 25 per cent of men and 31 per cent women had a BP over 150/90. Inconsistent recording of ECG and echocardiography made it hard to identify patients with left ventricular dysfunction. Forty six per cent of men and 37 per cent of women were either being prescribed Warfarin, or had contraindications to its use; of those on Warfarin 75.9 per cent have an international normalized ratio in range. Forty four per cent were treated with aspirin. People at high risk of stroke were no more likely to be treated with Warfarin or aspirin than those at moderate risk. Conclusions The rate of use of Warfarin remains low, and there is scope for better recording and management of risk factors particularly BP.