Atrial pacing and sensing characteristics in heart failure patients undergoing cardiac resynchronization therapy

Patients with heart failure and sinus rhythm undergoing cardiac resynchronization therapy (CRT) require the proper detection of atrial signals and reliable atrial pacing for AV-synchronous ventricular pacing. The study aim was to compare atrial pacing and sensing characteristics in patients with tra...

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Bibliographic Details
Published in:Europace (London, England) England), 2005-03, Vol.7 (2), p.165-169
Main Authors: Schuchert, Andreas, Aydin, Mohammed Ali, Israel, Carsten, Gaby, Gaby, Paul, Vince
Format: Article
Language:English
Subjects:
Aged
Cardiac Pacing, Artificial
Case-Control Studies
Female
Heart Atria - physiopathology
Heart Failure - physiopathology
Heart Failure - therapy
Humans
Male
Middle Aged
Pacemaker, Artificial
Sensory Thresholds
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Summary:Patients with heart failure and sinus rhythm undergoing cardiac resynchronization therapy (CRT) require the proper detection of atrial signals and reliable atrial pacing for AV-synchronous ventricular pacing. The study aim was to compare atrial pacing and sensing characteristics in patients with transvenous CRT and patients with standard pacing indications. The study group consisted of 31 heart failure patients with depressed left ventricular function and bundle branch block, and the control group of 124 patients with dual-chamber pacemakers because of standard pacing indications. The bipolar steroid-eluting atrial screw-in lead Tendril DX 1388 T (St. Jude Medical) was implanted and connected to pulse generators that provide similar diagnostic features. The unipolar pacing threshold at 0.4 ms duration, bipolar sensing threshold, and unipolar pacing impedance were determined at implantation and after 1, 3, and 6 months. At implantation, the atrial pacing threshold was significantly higher in the CRT group than in the control group, 1.07+/-0.99 V versus 0.74+/-0.36 V (P
ISSN:1099-5129
DOI:10.1016/j.eupc.2004.12.004