A Uniform Residual Tumor (R) Classification: Integration of the R Classification and the Circumferential Margin Status

Since the introduction of the TNM residual tumor (R) classification, the involvement of resection margins has been defined either as a microscopic (R1) or a macroscopic (R2) demonstration of tumor directly at the resection margin ("tumor transected"). The recognition of the importance of t...

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Bibliographic Details
Published in:Cancer 2009-08, Vol.115 (15), p.3483-3488
Main Authors: WITTEKIND, Christian, COMPTON, Carolyn, QUIRKE, Phil, NAGTEGAAL, Iris, MERKEL, Susanne, HERMANEK, Paul, SOBIN, Leslie H
Format: Article
Language:English
Subjects:
Biological and medical sciences
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Medical sciences
Neoplasm Staging - methods
Neoplasm, Residual - classification
Neoplasm, Residual - pathology
Rectal Neoplasms - pathology
Rectal Neoplasms - surgery
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Terminology as Topic
Tumors
Citations: Items that this one cites
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Summary:Since the introduction of the TNM residual tumor (R) classification, the involvement of resection margins has been defined either as a microscopic (R1) or a macroscopic (R2) demonstration of tumor directly at the resection margin ("tumor transected"). The recognition of the importance of the circumferential resection margin (CRM) in patients with rectal cancer patients raises the need for an alternative definition of resection margin involvement, namely, the importance of delineating tumor with a minimal distance from the CRM of
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.24320