Severity of disease as main predictor for mortality in patients with pyogenic liver abscess

Abstract Background The purpose of this study was to explore the relationship between severity of illness at admission and mortality of patients with pyogenic liver abscess (PLA). Methods Medical records from 298 PLA patients ≥18 years old were reviewed. Severity of illness at admission was evaluate...

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Published in:The American journal of surgery 2009-08, Vol.198 (2), p.164-172
Main Authors: Chen, Shiuan-Chih, M.D., Ph.D, Huang, Chi-Chou, M.D., Ph.D, Tsai, Shih-Jei, M.D, Yen, Chi-Hua, M.D., M.S, Lin, Ding-Bang, Ph.D, Wang, Po-Hui, M.D., Ph.D, Chen, Chun-Chieh, M.D., Ph.D, Lee, Meng-Chih, M.D., Ph.D., M.P.H
Format: Article
Language:English
Subjects:
Abdomen
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents - therapeutic use
Antibiotics
APACHE
Bacterial diseases
Bacterial diseases of the digestive system and abdomen
Biological and medical sciences
Classification
Confidence intervals
E coli
Epidemiology
Escherichia coli - isolation & purification
Escherichia coli Infections - complications
Fatalities
Female
Gases - metabolism
General aspects
Hospitals
Human bacterial diseases
Humans
Illnesses
Infections
Infectious diseases
Klebsiella Infections - complications
Klebsiella pneumoniae - isolation & purification
Laboratories
Liver
Liver Abscess, Pyogenic - mortality
Liver Abscess, Pyogenic - therapy
Male
Medical imaging
Medical records
Medical sciences
Middle Aged
Mortality
Multivariate Analysis
Patients
Phospholipase A
Physiology
Public health. Hygiene
Public health. Hygiene-occupational medicine
Pyogenic liver abscess
Regression analysis
Risk factor
Risk Factors
ROC Curve
Sensitivity
Sensitivity and Specificity
Severity of disease
Severity of Illness Index
Surgery
Tomography
Ultrasonic imaging
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Summary:Abstract Background The purpose of this study was to explore the relationship between severity of illness at admission and mortality of patients with pyogenic liver abscess (PLA). Methods Medical records from 298 PLA patients ≥18 years old were reviewed. Severity of illness at admission was evaluated with the Acute Physiology and Chronic Health Evaluation (APACHE) II and the simplified acute physiology score (SAPS) II scoring systems. Stepwise logistic regression and receiver-operating-characteristic curve analyses were performed. Results The case-fatality rate was 10%. Multivariate analysis showed that APACHE II ( P = .0004), SAPS II ( P = .0008), the presence of gas-forming abscess ( P
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2008.08.022