Use of cardiac resynchronization therapy to optimize beta-blocker therapy in patients with heart failure and prolonged QRS duration

A retrospective analysis was performed on 52 patients with heart failure to determine the change in β-blocker therapy after cardiac resynchronization therapy (CRT). After 6 months of CRT, the number of patients receiving β-blocker therapy increased from 36 to 44, with improved clinical outcomes and...

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Bibliographic Details
Published in:The American journal of cardiology 2005-04, Vol.95 (7), p.889-891
Main Authors: Aranda, Juan M., Woo, Gregory W., Conti, Jamie B., Schofield, Richard S., Conti, C. Richard, Hill, James A.
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - therapeutic use
Aged
Arrhythmias, Cardiac - complications
Arrhythmias, Cardiac - diagnosis
Arrhythmias, Cardiac - therapy
Beta blockers
Defibrillators, Implantable
Drug therapy
Electrocardiography
Female
Heart failure
Heart Failure - complications
Heart Failure - drug therapy
Humans
Male
Middle Aged
Retrospective Studies
Treatment Outcome
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Summary:A retrospective analysis was performed on 52 patients with heart failure to determine the change in β-blocker therapy after cardiac resynchronization therapy (CRT). After 6 months of CRT, the number of patients receiving β-blocker therapy increased from 36 to 44, with improved clinical outcomes and larger β-blocker doses, indicating that these 2 therapies may work together to improve outcomes by allowing the use of larger doses of β blockers while correcting ventricular dyssynchrony.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.12.023