Retroperitoneal Malignant Solitary Fibrous Tumor of the Small Pelvis Causing Recurrent Hypoglycemia by Secretion of Insulin-like Growth Factor 2

Abstract A 28-yr-old man presented with recurrent reduced consciousness, generalized seizures of unknown etiology, recurrent hypoglycemia, psychomotor retardation, and grade 2 ectasia of the left kidney. Abdominal computed tomography (CT) and positron emission tomography (PET) scans demonstrated a w...

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Bibliographic Details
Published in:European urology 2009-03, Vol.55 (3), p.739-742
Main Authors: Wagner, Sigrid, Greco, Francesco, Hamza, Amir, Hoda, Rashid M, Holzhausen, Hans Jürgen, Fornara, Paolo
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Humans
Hypoglycemia - etiology
Insulin-Like Growth Factor II - secretion
Kidneys
Male
Malformations of the urinary system
Medical sciences
Nephrology. Urinary tract diseases
Recurrence
Retroperitoneal Neoplasms - complications
Retroperitoneal Neoplasms - secretion
Solitary Fibrous Tumors - complications
Solitary Fibrous Tumors - secretion
Urology
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Summary:Abstract A 28-yr-old man presented with recurrent reduced consciousness, generalized seizures of unknown etiology, recurrent hypoglycemia, psychomotor retardation, and grade 2 ectasia of the left kidney. Abdominal computed tomography (CT) and positron emission tomography (PET) scans demonstrated a well-circumscribed suprapubic pelvic mass, measuring 18 × 15 × 11 cm, with involvement of para-aortic lymph nodes and dilatation of the left ureter suggestive of an extragonadal testicular tumor. We excised the tumor by laparotomy, and it was confirmed to be a solitary fibrous tumor (SFT). After surgery and R0 tumor resection, the patient had no further evidence of hypoglycemia or of recurrence.
ISSN:0302-2838
1873-7560
DOI:10.1016/j.eururo.2008.09.050