Myocardial Performance Index Derived From Brachial–Ankle Pulse Wave Velocity: A Novel and Feasible Parameter in Evaluation of Cardiac Performance

Background Right brachial pre-ejection period (rbPEP), brachial–ankle pulse wave velocity (baPWV), and right brachial ejection time (rbET) can be automatically determined from an ABI-form device. The aims of this study are to test the applicability of baPWV-derived myocardial performance index (MPI)...

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Bibliographic Details
Published in:American journal of hypertension 2009-08, Vol.22 (8), p.871-876
Main Authors: Su, Ho-Ming, Lin, Tsung-Hsien, Lee, Chee-Siong, Lee, Hsiang-Chun, Chu, Chun-Yuan, Hsu, Po-Chao, Voon, Wen-Chol, Lai, Wen-Ter, Sheu, Sheng-Hsiung
Format: Article
Language:English
Subjects:
Aged
Analysis of Variance
Ankle Brachial Index
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cardiovascular system
Echocardiography
Electrocardiography
Female
Heart - physiology
Heart Function Tests
Humans
Investigative techniques of hemodynamics
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Reproducibility of Results
ROC Curve
Ventricular Function, Left - physiology
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Summary:Background Right brachial pre-ejection period (rbPEP), brachial–ankle pulse wave velocity (baPWV), and right brachial ejection time (rbET) can be automatically determined from an ABI-form device. The aims of this study are to test the applicability of baPWV-derived myocardial performance index (MPI) (defined as the ratio of rbPEP divided by its own s.d. + baPWV divided by its own s.d. to rbET divided by its own s.d.) as an indicator of combined left ventricular (LV) systolic and diastolic functions. Methods A sum of 215 patients were consecutively included. The rbPEP, baPWV, and rbET were measured using an ABI-form device and LV function was determined by echocardiography. Results After a multivariate analysis, diastolic blood pressure (β = 0.220, P < 0.001), LV ejection fraction (LVEF) (β = −0.291, P < 0.001), transmitral E wave velocity (E) (β = −0.106, P = 0.032), early diastolic mitral annular velocity (Ea) (β = −0.142, P = 0.009), and ET obtained by tissue Doppler echocardiography (β = −0.397, P < 0.001) were the major determinants of baPWV-derived MPI. The area under the curve for rbPEP, baPWV, rbET, rbPEP/rbET, and baPWV-derived MPI in prediction of Ea 10, or LVEF
ISSN:0895-7061
1941-7225
1879-1905
DOI:10.1038/ajh.2009.94