Surgical treatment of skull fibrous dysplasia

• Published in: Surgical neurology 2009-08, Vol.72, p.S17-S20
• Main Authors: Lei, Peng, MD, Bai, Hongtao, MD, Wang, Yu, MD, Liu, Qi, MD
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Biological and medical sciences; Craniotomy - methods; Decompression, Surgical - methods; Facial Bones - pathology; Facial Bones - surgery; Female; Fibrous dysplasia; Fibrous Dysplasia of Bone - complications; Fibrous Dysplasia of Bone - surgery; Follow-Up Studies; Humans; Male; Medical sciences; Middle Aged; Neurology; Neurosurgery; Neurosurgical Procedures - methods; Optic Nerve - surgery; Paranasal Sinuses - surgery; Skull; Skull - pathology; Skull - surgery; Skull base reestablishment; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Treatment Outcome; Young Adult
• ISSN: 0090-3019; 1879-3339
• DOI: 10.1016/j.surneu.2008.03.041

Abstract Background Fibrous dysplasia of the skull is difficult to manage when the cranial nerves, skull base, and face are involved. The procedure for the surgical treatment of this lesion needs to be studied clinically because of the low incidence rate and its operative complicacy. Faced with this, combined with our clinical experience, we explore the surgical strategy and operative procedures of the skull fibrous dysplasia. Methods Twelve patients with skull fibrous dysplasia have been studied with neuroimaging and underwent operative removal of the lesion and cranioplasty and/or reestablishment of the skull base. Results Excellent operating outcome was obtained in 9 cases and good in 3 based on the evaluation of the lesion removal, cranioplasty, skull base reestablishment, and cranial nerve function recovery. Conclusion Surgical treatment is suitable for a patient whose lesion damages his or her cranial nerve function and/or appearance. In general, removal of the lesion, cranioplasty, and/or skull base reestablishment can be finished in 1 stage.