Impaired memory and olfactory performance in NaSi-1 sulphate transporter deficient mice

In the present study, NaSi-1 sulphate transporter knock-out (Nas1-/-) mice, an animal model of hyposulphataemia, were examined for spatial memory and learning in a Morris water maze, and for olfactory function in a cookie test. The Nas1-/- mice displayed significantly (P

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Bibliographic Details
Published in:Behavioural brain research 2005-04, Vol.159 (1), p.15-20
Main Authors: DAWSON, Paul Anthony, STEANE, Sarah Elizabeth, MARKOVICH, Daniel
Format: Article
Language:English
Subjects:
Animal
Animals
Biological and medical sciences
Cation Transport Proteins - genetics
Cation Transport Proteins - physiology
Escape Reaction - physiology
Fundamental and applied biological sciences. Psychology
Learning. Memory
Male
Memory
Memory - physiology
Memory Disorders - physiopathology
Mice
Mice, Knockout
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Reaction Time - genetics
Reaction Time - physiology
Reversal Learning - physiology
Smell - genetics
Smell - physiology
Spatial Behavior - physiology
Symporters - genetics
Symporters - physiology
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Summary:In the present study, NaSi-1 sulphate transporter knock-out (Nas1-/-) mice, an animal model of hyposulphataemia, were examined for spatial memory and learning in a Morris water maze, and for olfactory function in a cookie test. The Nas1-/- mice displayed significantly (P
ISSN:0166-4328
1872-7549
DOI:10.1016/j.bbr.2004.09.020