Selective Portal Vein Clamping for Radiofrequency Ablation of Hepatocellular Carcinoma With Portal Vein Invasion

Surgical resection provides potential cure for patients with hepatocellular carcinoma. Unfortunately, resection is suitable in only about 10–37% of patients because of the limited hepatic functional reserve from the underlying chronic liver disease in the majority of patients. Survival of patients w...

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Bibliographic Details
Published in:Journal of gastrointestinal surgery 2005-04, Vol.9 (4), p.489-493
Main Authors: Chok, Kenneth S., Ng, Kenneth C., Lam, Chi Ming, Ng, Kelvin K., Poon, Ronnie T., Fan, Sheung Tat
Format: Article
Language:English
Subjects:
Cancer
Carcinoma, Hepatocellular - diagnostic imaging
Carcinoma, Hepatocellular - pathology
Carcinoma, Hepatocellular - surgery
Catheter Ablation
Hepatocellular carcinoma
Humans
Liver cancer
Liver cirrhosis
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - pathology
Liver Neoplasms - surgery
Male
Middle Aged
Neoplasm Invasiveness
Portal Vein - diagnostic imaging
Portal Vein - pathology
Portal Vein - surgery
portal vein invasion
radiofrequency ablation
Tomography, X-Ray Computed
Tumors
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Summary:Surgical resection provides potential cure for patients with hepatocellular carcinoma. Unfortunately, resection is suitable in only about 10–37% of patients because of the limited hepatic functional reserve from the underlying chronic liver disease in the majority of patients. Survival of patients with unresectable diseases, especially those with portal vein tumor invasion, remains very poor. Radiofrequency ablation (RFA) is a form of locoregional therapy that allows a selected group of previously inoperable patients to be treated. However, problems with RFA leading to induced portal vein thrombosis have been reported in the literature. Nevertheless, patients with portal vein tumor invasion may be considered for radiofrequency tumor ablation to improve survival. We report the case of a patient with hepatocellular carcinoma with left portal vein invasion. Complete tumor ablation was achieved after RFA with left portal vein clamping. He remained disease free both radiologically and biochemically 6 months after the operation.
ISSN:1091-255X
1873-4626
DOI:10.1016/j.gassur.2004.09.056